Portfolio

1upHealth provides data interoperability between healthcare systems at a very low cost, fractions of a cent per API call, utilizing the latest FHIR® standards, and patient-authorized access, to ensure the best insights at the lowest costs across healthcare providers for low-income, diverse, and vulnerable populations. Learn more at https://1up.health.

Nascent biotech company harnessing emerging science on the importance of Glia in brain disease. Abelian Therapeutics was acquired in September 2020.

ABK Biomedical is organized to research, develop and commercialize breakthrough medical device therapies to improve treatment outcomes and the lives of patients with benign and malignant hypervascular tumors. Specifically, ABK holds intellectual property in the focus area of inorganic polymer microspheres, targeted at the growing field of embolotherapy within the Interventional Radiology/Interventional Oncology medical disciplines. The company possesses advanced intellectual capital and its own R&D and manufacturing facilities for developing and commercializing unique, breakthrough embolotherapy products. Learn more at www.abkmedical.com.

Acacia Pharma (EURONEXT:ACPH) is a commercially driven hospital pharmaceutical group focused on the development and commercialisation of new nausea and vomiting treatments for surgical and cancer patients. Acacia was acquired by Eagle Pharmaceuticals in 2022.

Accuri Cytometers was a life sciences tools company that democratized flow cytometry for medical and pharmaceutical research. Accuri Cytometers was acquired by Becton Dickinson.

Aclaris Therapeutics, Inc. (NASDAQ:ACRS) is a dermatologist-led biopharmaceutical company committed to identifying, developing and commercializing innovative therapies to address significant unmet needs in aesthetic and medical dermatology and immunodermatology. Learn more at www.aclaristx.com.

Adagene (Nasdaq: ADAG) is an antibody discovery and engineering company with proprietary Smart Antibody Technology, which increases success rates, substantially accelerates time to market, and reduces the costs associated with developing a therapeutic antibody. Learn more at www.adagene.com.

Adaptimmune (NASDAQ: ADAP) is a cellular therapeutics company developing affinity enhanced T-cell receptor (TCR) engineered T-cells to treat solid tumor and hematological cancers. Learn more at www.adaptimmune.com.

Adela (formerly DNAMx) is focused on the detection of cancer and other high-morbidity, high-mortality conditions through a routine blood test. The company’s genome-wide methylation analysis technology has the unique ability to distinguish the most-highly informative (methylated) regions of the genome from non-informative regions and preferentially target those informative regions for sequencing.  Learn more at www.adelabio.com.

Aerium Therapeutics is dedicated to epidemic and pandemic preparedness through the discovery and development of antibodies and small molecule antivirals against SARS-CoV-2 and other epidemic and pandemic threats. The Aerium Therapeutics team brings world-class scientists and biotechnology veterans together with experienced investors, with operations in Boston, MA and Lausanne, Switzerland. Learn more at www.aeriumtx.com.

Affinia Therapeutics is a gene therapy company with a platform for rationally designed adeno-associated virus (AAV) vectors and gene therapies and a mission to develop transformative medicines for devastating diseases. Learn more at www.affiniatx.com.

Airespace was a market leader in the design and development of wireless networking platforms that support business-critical applications. The company’s AireWave Director(TM) Software provided dynamic RF intelligence for network optimization, air tight security, seamless mobility, and support for real-time applications, such as voice. With Airespace, enterprises could maximize the value of mobility by putting the air space to work. Airespace was acquired by Cisco in 2005.

Alibaba is a Chinese e-commerce company that provides consumer-to-consumer, business-to-consumer and business-to-business sales services via web portals. Alibaba (NYSE:BABA) went public in 2014. Learn more at www.alibaba.com.

Alternative Bio’s mission is to translate the discovery of novel protein synthesis regulatory nodes into first-in-class precision medicines to treat the most challenging cancers. The company’s vision is to establish itself as a global pioneer in this new research space as it advances breakthrough therapies to benefit cancer patients worldwide.

Amphora Medical was a medical device technology company developing minimally invasive products to restore the quality of life of people suffering from Overactive Bladder Syndrome.

AmplifyMD is a turnkey specialty access platform connecting the over 3,300 medical institutions with a lack of specialty access – often in rural or small regions of the United States – to a network of leading specialists. The company provides both the clinical team as well as the software to streamline and automate virtual care delivery and billing workflows and integrates seamlessly with hospitals’ existing EHRs. Learn more at www.amplifymd.com.

Apellis Pharmaceuticals, Inc. (NASDAQ: APLS) is a clinical-stage biopharmaceutical company focused on the development of novel therapeutic compounds to treat disease through the inhibition of the complement system, at the level of C3, the central protein in the complement cascade. Learn more at www.apellis.com.

AppliedVR is a leader in digital therapeutics, pioneering virtual reality-based treatments that address the complexity of chronic pain with a mission to empower patients with the tools to live life, beyond chronic pain. Rooted in cognitive behavioral therapy and mindfulness, AppliedVR’s EaseVRx is the first VR-based prescription therapeutic to receive Breakthrough Device Designation by the FDA.  Learn more at www.appliedvr.io.

AppsFlyer is a mobile advertising measurement platform that allows app marketers to measure their user acquisition campaigns in real-time. Learn more at www.appsflyer.com.

Argyle provides a single global access point to employment data. From that access point, any business can process verifications, gain real-time transparency into earnings as well as view and update worker profile details. By removing the barriers between a worker, the companies they make money from, and the business they buy services and products from Argyle has reimagined how employment data can be used. Argyle was founded in 2018 and operates out of New York. Learn more at www.argyle.io.

The company specializes in personalized full-cycle cancer treatments and management, from prevention and early test of symptoms to the adoption of advanced cancer treatment methods. Learn more at www.arion.care.

Artemis Health helps companies utilize their data to optimize their benefits programs while minimizing their spend. The Artemis Platform provides customers with actionable data on their benefits programs, opportunities and gaps, and easy-to-use tools to help them make great decisions. Artemis Health was acquired by Nomi Health in 2022.

Arvelle Therapeutics is a biopharmaceutical company with the mission of bringing innovative solutions to patients suffering from CNS disorders. Arvelle is responsible for the development and commercialization of cenobamate, an investigational antiepileptic drug, in the European market.  Arvelle Therapeutics was acquired by Angelini Pharma in January 2021.

Ashby exists to deliver a new standard of recruiting software to enable hiring excellence. It’s all-in-one recruiting platform enables high growth companies to hire more efficiently by combining features for the entire recruiting process, from sourcing to offer, with advanced analytics and automation. Learn more at www.ashbyhq.com.

Atalanta Therapeutics is a biotechnology company pioneering new treatment options for neurodegenerative diseases by utilizing its proprietary RNA interference platform.  Learn more at www.atalantatx.com.

Audacy is a space communications service provider delivering continuous connectivity and data in real time to spacecraft operators. With a spectrum license granted by the U.S. Federal Communications Commission (FCC) in June 2018, and by deploying a network of medium Earth orbit relay satellites and ground facilities, Audacy will provide the first commercially available inter-satellite data relay network, enabling seamless low-Earth orbit coverage and always-on connectivity from ground to lunar orbit. To learn more, visit https://audacy.space.

Avalyn is a biopharma company committed to developing improved therapies for the treatment of idiopathic pulmonary fibrosis (IPF) and other severe respiratory diseases. Learn more at www.avalynpharma.com.

AvantStay delivers exceptional, unique stays for group travelers. The company has built a tech-enabled millennial hospitality brand to be the new standard for group experience.  Unlike typical short-term rentals, Avantstay controls the entire guest experience. This allows the company to ensure the quality of a guest’s stay will be consistent across all homes and to deliver hotel-level comfort in an authentic differentiated setting. Learn more at avantstay.com.

AviadoBio is a pioneering gene therapy company focused on developing and delivering transformative medicines for people living with neurodegenerative disorders. Learn more at www.aviadobio.com.

Avidity Biosciences (NASDAQ: RNA)  is a biotech company pioneering a new class of precision medicines – Antibody-siRNA Conjugates (ASC™) – which combine the strengths of monoclonal antibodies and siRNA-based therapeutics to overcome barriers to the delivery of siRNA and target genetic drivers of disease. Learn more at www.aviditybiosciences.com.

Avivomed, is a medical device company developing innovative neuromodulation technology to treat large disease populations.  Learn more at www.avivomed.com.

Axoni is a New York-based technology firm that specializes in distributed ledger infrastructure with clients that include many of the world’s largest financial institutions and capital markets infrastructure companies. Founded in 2013 by a team of distributed ledger technology experts, the company offers blockchain infrastructure, distributed application development, and workflow automation tools. Learn more at www.axoni.com.

b-ONE Ortho Corp. is an emerging orthopedic technology company dedicated to the development of innovative orthopedic healthcare solutions that restore patient mobility and improve surgical outcomes. Every day we are committed to becoming the most credible choice for orthopedic products worldwide. Learn more at http://www.b1.co/.

Zhejiang Bang Er Medical Investment Management Co., Ltd. is a leading private medical service provider that operates several private hospitals specializing in orthopedic care and related services in China. Learn more at www.zjbanger.com.

Beam Therapeutics (NASDAQ: BEAM) is pioneering the use of CRISPR base editing to develop precision genetic medicines that treat disease, one letter at a time. Learn more at www.beamtx.com.

Benchling is the leader in cloud-based informatics for life science R&D. The company offers a unified R&D platform purpose-built for biologics, including solutions for Lab Notebook, Molecular Biology, Bioregistration, Sample Tracking, Requests and Workflow Management. Benchling is used by over 100,000 scientists globally throughout multinational pharmaceutical corporations, emerging biotechnology companies, and major research institutions. Learn more at https://benchling.com/.

BenchSci exponentially increases the speed and quality of life-saving research by empowering scientists with the world’s most advanced biomedical artificial intelligence to run more successful experiments. Learn more at www.benchsci.com.

Better Life Medical is a fully-integrated hearing aid manufacturer developing and commercializing novel digital programmable hearing aid solutions for the Chinese market. Learn more at www.goblm.com.cn/.

Better Life Partners is a provider of high-quality, integrated medical and behavioral healthcare to people not well served by the traditional system. The company’s offerings include group therapy sessions with a special curriculum that utilizes evidence-based cognitive and dialectical behavioral therapy to build a sense of community and purpose toward a better life, enabling patients of substance abuse to be provided with aid and support to get sober.  Learn more at www.betterlifepartners.com.

Bicara Therapeutics is a clinical-stage biotechnology company developing first-in-class biologics engineered to bring together the precision of targeted therapy and the power of tumor modulators. The company’s bifunctional antibodies are designed to deliver an immunomodulatory payload directly to the tumor microenvironment to ramp up immune cell activity, potentially offering long-lasting efficacy. Learn more at www.bicara.com

Bikam Pharmaceuticals is a drug discovery company focused on developing novel therapies for diseases of the eye with exceptionally high unmet medical need. Bikam Pharmaceuticals was acquired by Shire.

BioConnect Systems was a medical device company that developed a CE-Marked product for improving dialysis access  surgery. Learn more at www.bioconnectsystems.com.

BioPalette is a life science start up formed out of Kobe University developing base editing technology for a range of applications. Learn more at www.biopalette.co.jp.

BioRegen Biomedical is a fully integrated medical product company based on a proprietary technology platform. BioRegen is developing and commercializing high quality hyaluronic acid (“HA”) based products for the Chinese market. Learn more at www.bioregenmed.com.

BlackDuck secures and manages open source software worldwide, eliminating open source security vulnerabilities & license compliance pain. BlackDuck was acquired by Synopsys in 2017.  Learn more at www.blackducksoftware.com.

Blispay makes financing easy and accessible for merchants and shoppers. The company provides point-of-sale financing with no integration and no additional costs to the merchant, ultimately helping businesses increase sales while providing consumers with better buying options everywhere they shop. Approved shoppers will additionally receive the Blispay credit card and continue to receive no interest, no payments on all purchases over $199 if paid in full in six months, plus automatic 2 percent cash back everywhere Visa is accepted. Located in Baltimore, Blispay’s team includes pioneers of the financing industry with experience that spans banking, credit and retail.  Blispay was acquired by Alliance Data in 2019. Learn more at www.blispay.com.

Blue Rabbit is a chronic disease management platform designed to coordinate diagnostics, medications and nutrition for animal patients. The company enables the effortless administration of healthcare through an ecosystem of technology driven solutions and services. Learn more at www.bluerabbit.vet.

Blueprint Medicines (NASDAQ: BPMC) is a precision therapy company striving to improve human health. Learn more at www.blueprintmedicines.com.

Buoy is an online symptom and cure checker that uses an intelligent algorithm backed by medical data to diagnose patients. Learn more at www.buoyhealth.com.

Burro, formally known as Augean Robotics, is a Philadelphia-based robotics company building an autonomous platform designed to free growers and their workforce from tedious tasks, while building the modular base for greater autonomy. Founded in 2017, the company offers the only fully autonomous, plug-and-play collaborative farming robot on the market. To learn more Burro, visit burro.ai.

Canary Technologies is modernizing the hotel tech stack, with the first mobile web end-to-end Guest Management System, digitizing everything from post-booking through checkout. Trusted by thousands of hotels in more than 65 countries, including Four Seasons, Choice Hotels, Standard Hotels and Ace Hotel Group, Canary’s solutions help hotels eliminate paper processes, boost revenue with upsells, raise staff efficiency, ensure PCI compliance, improve the guest experience, and reduce chargebacks and payment fraud. Learn more at canarytechnologies.com.

Canoe’s mission is to unlock efficiencies in alternative investment processes by introducing purpose-built automation into the workflows of institutional investors, asset servicers, capital allocators and wealth managers. Learn more at canoeintelligence.com.

Capital Rx is built around the mission of changing the way prescription drugs are priced and patients are serviced. A health technology company daring to reimagine the healthcare industry, Capital Rx is executing on that mission with its enterprise pharmacy platform JUDI™, which connects every aspect of the pharmacy ecosystem in one platform, enabling patient engagement and increasing efficiency to achieve the highest standards of clinical care. Learn more at www.cap-rx.com.

Caplin Point Laboratories Limited is a fast growing pharmaceutical company with a unique business model catering predominantly to emerging markets of Latin America and Africa. Caplin Point Laboratories Limited has state of the art manufacturing facilities that cater to a complete range of finished dosage forms. The Company has also entered regulated markets such as US through its Wholly Owned Subsidiary Caplin Steriles Limited. Learn more at www.caplinpoint.net.

CardioKine is a pharmaceutical company focused on the development of lixivaptan, an oral compound under development for the potential treatment of hyponatremia in patients with congestive heart failure. CardioKine was acquired by Cornerstone Therapeutics.

CareStack™ is a cloud based platform that combines dental practice management, patient engagement and data analytics. Learn more at www.carestack.com.

Caribou (NASDAQ:CRBU) is a leading company in CRISPR genome editing founded by pioneers of CRISPR-Cas9 biology. Caribou’s proprietary technologies put the company at the forefront of the development of new medical therapies. Learn more at www.cariboubio.com.

Carrot Fertility is a global fertility benefits provider for employers, built to support employees through their entire fertility healthcare journey. Companies use Carrot to customize a fertility benefit that provides employees financial, medical, and emotional support as they pursue parenthood, resulting in better clinical outcomes. Carrot’s program includes egg freezing, in vitro fertilization (IVF), adoption, donor and gestational carrier services; Carrot Rx, a premium pharmacy experience, at significant savings; Carrot Pregnancy; and the Carrot Card®, a flexible fertility benefits debit card employees can use to pay for their care. Learn more at www.get-carrot.com.

Castle is the security industry’s first zero-configuration solution for account takeover (ATO) protection. Learn more at www.castle.io.

Castor is a leading provider of decentralized and hybrid clinical trial solutions to democratize research. With the highest rated eClinical platform for decentralized and hybrid clinical trials, Castor’s plug and play platform offers rapid deployment at scale, enabling researchers to create a trial in a matter of clicks, with easy enrollment, consent and real-world data capture. Learn more at www.castoredc.com.

Centivo is a new type of self-funded health plan built specifically for employers and their employees and families.  The Company targets zero healthcare trend and improved healthcare outcomes by rewarding members and providers for smart choices and actions while delivering an exceptional member experience. Centivo serves as a health plan or third-party administrator (TPA) for employers and partners closely with local health plans and TPAs to enhance their offerings. Learn more at www.centivo.com.

CHARM Therapeutics is a 3D deep-learning research Company discovering and developing transformational medicines. Based on the award-winning discoveries of David Baker in protein-folding, CHARM has developed a proprietary technology based on the first rapid, accurate protein/ligand co-folding algorithm. The Company’s mission is to use these insights to address challenging targets in cancer and other disease areas and discover and develop new drugs against these targets. Learn more at www.charmtx.com.

Checkmate Pharmaceuticals (NASDAQ: CMPI) is a clinical stage company pursuing a novel approach to specifically activating the innate and adaptive arms of the immune system to recognize and ultimately destroy tumor cells. Checkmate Pharmaceuticals was acquired by Regeneron (NASDAQ:REGH) in 2022.

Cipla Health focuses on developing and commercializing products in the consumer healthcare and over-the-counter categories. Learn more at www.ciplahealth.in.

Cloudant offered a distributed NoSQL database-as-a-service (DBaaS) for developers creating web and mobile applications. Cloudant was acquired by IBM in 2014.

Codeship operates a cloud-based platform that helps software developers test and deploy their code more efficiently through continuous integration (CI) and continuous deployment (CD). Codeship was acquired by Cloudbees in 2018. Learn more at codeship.com.

Cogent Biosciences (NASDAQ:COGT) (formerly Unum Therapeutics) has built an antibody-coupled T-cell receptor (ACTR) platform that, when combined with tumor-specific antibodies, directs an individual’s cytotoxic T-lymphocytes (CTLs) to kill tumor cells. Learn more at www.cogentbio.com.

Coherus Biosciences (NASDAQ: CHRS) is a biosimilar-focused, biologics platform company with the cutting-edge analytics, process science, and clinical and regulatory capabilities to develop and commercialize high-quality biosimilar therapeutics worldwide. Learn more at www.coherus.com.

Comanche Biopharma is a maternal and fetal medicine biopharmaceutical company working to lower the risks of pregnancy and premature births worldwide. We are currently developing the world’s first treatment for preeclampsia, which affects more than 10 million women every year. Learn more at www.comanchebiopharma.com.

Compass Therapeutics (NASDAQ: CMPX) is comprehensively drugging the tumor-immune synapse with human antibodies against over 50 cell surface and soluble targets. Learn more at www.compasstherapeutics.com.

ConnexPay is revolutionizing the payment distribution process by offering a combined merchant acquiring and virtual card issuing solution for mid-sized companies. The company’s technology simplifies an antiquated workflow, eliminates the need for pre-funded accounts, reduces supplier risk and the cost of accepting card payments while safeguarding consumer spend. Backed by  F-Prime Capital and BIP Capital, ConnexPay is becoming the industry leader in payments for industries historically viewed as high risk to payment providers.  Learn more at www.connexpay.com.

CORE provides high-end diagnostics services for disease stratification and therapy selection. Learn more at www.corediagnostics.in.

Cúram Software was a leading provider of solutions for social program management organizations. Cúram Software solutions helped leaders innovate across services and organizations to meet and exceed citizen expectations and support improved outcomes. The company was acquired by IBM in 2011.

Curegenix is a Chinese leader in discovery and development of novel drugs in stem cell related diseases. Learn more at www.curegenix.com.

Curie.Bio is a founder-focused seed-stage venture firm combined with an industry-grade therapeutics accelerator focused on one thing: helping entrepreneurial founders launch viable therapeutics companies. Curie.Bio does this by giving founders access to a team of the world’s best drug hunters and drug makers, seed capital, and best-of-breed services – everything a founder needs to get from concept to a compelling quality dataset that enables an awesome Series A financing. In a nutshell, we want founders in control of their own company and focused on their area of expertise and creativity, while we help make the rest happen smoothly.

Cygnus Hospitals is an asset-light chain of 10 hospitals based in North India, focusing on select higher-secondary and tertiary-care specialties. Learn more at www.cygnushospitals.com.

Cytek Biosciences Inc.  (NASDAQ: CTBK) is a leading flow cytometry solution provider that provides compact, affordable instruments with high multiplexing capabilities. Learn more at www.cytekbio.com.

Deal Engine is a Miami-based travel software company, with a mission to bring digital transformation to the travel industry. Utilizing proprietary AI and APIs, Deal Engine brings automation to travel, eliminating manual processes, and making sure people spend their time where they generate more value. Learn more at deal-engine.com.

Denali Therapeutics (NASDAQ:DNLI) is dedicated to defeating neurodegenerative diseases through rigorous therapeutic discovery and development. Learn more at www.denalitherapeutics.com.

Devoted Health is building a tech-enabled health insurance and clinical services solution focused on dramatically improving health care for seniors in the U.S. Learn more at www.devoted.com.

Dimension Therapeutics was a leader in the development of AAV (adeno-associated virus) gene therapies for rare disease. Dimension Therapeutics was acquired by Ultragenyx Pharmaceuticals (NASDAQ:RARE).

Doceree is the first global network of HCP-only platforms for programmatic messaging. Doceree facilitates messaging between life sciences brands and healthcare professionals (HCPs) through an extensive global network of digital endemic and point-of-care platforms to programmatically deliver at scale accurate and transparent messages to HCPs. Learn more at www.doceree.com.

Eleos is pioneering CareOps Automation. By consolidating the entire behavioral care workflow — everything from progress notes all the way to session intelligence— clinicians are freed from time-consuming operational burdens. Eleos takes care of CareOps, honing in on automating operational necessities, including all documentation, compliance administration as well as providing deep clinical insights through session intelligence. Eleos makes evidence-based behavioral care a reality so clinicians, providers, and networks can measurably and comparatively track treatment and progress. Learn more at eleos.health.

Elucidata was founded in 2015 by University of Chicago and MIT graduate Dr. Abhishek Jha and IIT Delhi alumnus Swetabh Pathak. The company’s cutting-edge platform Polly operates on unique Bio-NLP technology that cleans and links 26+ R&D data types and caters to companies in various stages of their drug discovery process. The platform helps data science teams scale by providing them 70 TB of ML-Ready biomedical data, from ~30 public and proprietary sources. Today, 3 of the top 10 pharmaceutical companies are using Polly to fast track their R&D initiatives. Learn more at www.elucidata.io.

Embark Veterinary, Inc. launched in 2015 with a mission to end preventable disease in dogs. An Embark Dog DNA Test enables pet owners to learn about their dog’s breed, ancestry, health, and what diseases may be in the future – all with a simple cheek swab. By using 100 times more genetic information than any other test available, the company offers the most accurate results on the market. Embark was started by two brothers, Adam and Ryan Boyko, who have a passion for scientific research and a lifelong love of dogs. Embark is an official research partner with Cornell University College of Veterinary Medicine.  Learn more at www.embarkvet.com.

Engooden Health (formerly Cohort)  offers payers and providers scalable, technology-enabled services for patients living with chronic conditions.. Learn more at www.engooden.com.

Ensoma is expanding the reach of the curative power of genomic medicine by pioneering a next-generation in vivo approach using its Engenious™ vectors. Ensoma’s vectors are designed to deliver a diverse range of gene modification technologies without the need for stem cell collection or prior myeloablative conditioning (e.g. chemotherapy). Learn more at www.ensoma.com.

Enzene is an innovation-driven biotech company a subsidiary of Alkem Laboratories Ltd. (one of the top five pharmaceutical companies in India*) located in Pune, India. Enzene’s focus lies in producing biosimilars, novel biologics, synthetic peptides and phytopharmaceuticals. Enzene also offers a range of biologics CDMO and CMO services with capabilities from clone development up to GMP manufacturing supported by bio-reactor capacities ranging from 20 litres to 2000 litres.

Equip delivers modern eating disorder treatment through family-based care that promises lasting recovery at home. Created by experts in the field and people who’ve been there, Equip provides each patient with a five-person dedicated care team including a therapist, dietician, physician, and peer & family mentor. Learn more at www.equip.health.

Eris Exchange is an interest rate swaps trading venue that provides the flexibility of OTC swaps within a futures contract, helping institutions manage the complexities of Dodd Frank derivatives regulations. Learn more at www.erisfutures.com.