Category

Sector

Region

Status

  • 1Money is a stablecoin and an associated blockchain-based payment network. 1Money is building a regulated global transaction layer and yield-generating stablecoin for businesses that is efficient, cheap, and composable.

  • 1upHealth provides data interoperability between healthcare systems at a very low cost, fractions of a cent per API call, utilizing the latest FHIR® standards, and patient-authorized access, to ensure the best insights at the lowest costs across healthcare providers for low-income, diverse, and vulnerable populations. Learn more at https://1up.health.

  • Nascent biotech company harnessing emerging science on the importance of Glia in brain disease. Abelian Therapeutics was acquired in September 2020.

  • ABK Biomedical is organized to research, develop and commercialize breakthrough medical device therapies to improve treatment outcomes and the lives of patients with benign and malignant hypervascular tumors. Specifically, ABK holds intellectual property in the focus area of inorganic polymer microspheres, targeted at the growing field of embolotherapy within the Interventional Radiology/Interventional Oncology medical disciplines. The company possesses advanced intellectual capital and its own R&D and manufacturing facilities for developing and commercializing unique, breakthrough embolotherapy products. Learn more at www.abkmedical.com.

  • Acacia Pharma (EURONEXT:ACPH) is a commercially driven hospital pharmaceutical group focused on the development and commercialisation of new nausea and vomiting treatments for surgical and cancer patients. Acacia was acquired by Eagle Pharmaceuticals in 2022.

    • Category

      • Therapeutics
    • Status

      • Acquired
      • Public
    • Location

      Cambridge, United Kingdom

    • Year Invested

      2013

    • Team

  • Accuri Cytometers was a life sciences tools company that democratized flow cytometry for medical and pharmaceutical research. Accuri Cytometers was acquired by Becton Dickinson.

  • Aclaris Therapeutics, Inc. (NASDAQ:ACRS) is a dermatologist-led biopharmaceutical company committed to identifying, developing and commercializing innovative therapies to address significant unmet needs in aesthetic and medical dermatology and immunodermatology. Learn more at www.aclaristx.com.

  • Adagene (Nasdaq: ADAG) is an antibody discovery and engineering company with proprietary Smart Antibody Technology, which increases success rates, substantially accelerates time to market, and reduces the costs associated with developing a therapeutic antibody. Learn more at www.adagene.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Suzhou, China

    • Year Invested

      2011

    • Team

  • Adaptimmune (NASDAQ: ADAP) is a cellular therapeutics company developing affinity enhanced T-cell receptor (TCR) engineered T-cells to treat solid tumor and hematological cancers. Learn more at www.adaptimmune.com.

  • Adcentrx is a biotechnology company focused on accelerating breakthroughs in protein conjugate therapeutic development for cancer and other life-threatening diseases. By combining the targeting precision of biologics and the disease-fighting power of small molecule payloads, Adcentrx strives to develop next-generation targeted therapies for improving patient treatment options. Learn more: https://www.adcentrx.com/

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      San Diego, CA and Shanghai, China

    • Year Invested

      2023

    • Team

  • Adela (formerly DNAMx) is focused on the detection of cancer and other high-morbidity, high-mortality conditions through a routine blood test. The company’s genome-wide methylation analysis technology has the unique ability to distinguish the most-highly informative (methylated) regions of the genome from non-informative regions and preferentially target those informative regions for sequencing.  Learn more at www.adelabio.com.

  • Aera Therapeutics is a biotechnology company leveraging its proprietary protein nanoparticle (PNP) delivery platform to unlock the full potential of genetic medicines. Aera’s platform, based on endogenous human proteins, is being developed to address the limitations of today’s delivery technologies and to expand the reach of genetic medicines to different tissues and applications, in order to benefit more patients across more disease areas. Aera’s licensed technology also includes a therapeutic enzyme platform based on the discovery of novel, compact and programmable gene editing enzymes. Aera is headquartered in Boston and has raised $193 million to date from leading life sciences investors. To learn more, please visit www.aeratx.com.

  • Aerium Therapeutics is dedicated to epidemic and pandemic preparedness through the discovery and development of antibodies and small molecule antivirals against SARS-CoV-2 and other epidemic and pandemic threats. The Aerium Therapeutics team brings world-class scientists and biotechnology veterans together with experienced investors, with operations in Boston, MA and Lausanne, Switzerland. Learn more at www.aeriumtx.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Boston, MA and Lausanne, CH

    • Year Invested

      2021

    • Team

  • Affinia Therapeutics is a gene therapy company with a platform for rationally designed adeno-associated virus (AAV) vectors and gene therapies and a mission to develop transformative medicines for devastating diseases. Learn more at www.affiniatx.com.

  • Airespace was a market leader in the design and development of wireless networking platforms that support business-critical applications. The company’s AireWave Director(TM) Software provided dynamic RF intelligence for network optimization, air tight security, seamless mobility, and support for real-time applications, such as voice. With Airespace, enterprises could maximize the value of mobility by putting the air space to work. Airespace was acquired by Cisco in 2005.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      San Jose, CA

  • Albert Invent empowers organizations to accelerate innovation with its state-of-the-art R&D platform. Built for chemistry and materials science, and powered by AI and Machine Learning, Albert’s collaborative, secure end-to-end platform delivers data insights and tools throughout the R&D process to accelerate speed to market. Albert is being utilized by some of the largest companies in the industry, along with emerging startups around the world. Learn more at https://www.albertinvent.com/

  • Alibaba is a Chinese e-commerce company that provides consumer-to-consumer, business-to-consumer and business-to-business sales services via web portals. Alibaba (NYSE:BABA) went public in 2014. Learn more at www.alibaba.com.

    • Category

      • FinTech
    • Status

      • Public
    • Location

      Hangzhou, China

  • Alluvial is a software development company supporting the development of the Liquid Collective protocol. Alluvial is focused on the overall growth and maturity of the ecosystem by fostering participation in proof of stake blockchains. Learn more at alluvial.finance.com.

  • AlphaGen Therapeutics is a radiopharmaceutical company focused on the discovery, development and commercialization of innovative targeted radioligand therapies (RLTs). Leveraging its cutting-edge technology platform, the company aims to develop targeted RLTs for patients in China and around the world. Learn more: www.alphagentx.com/

  • Alternative Bio’s mission is to translate the discovery of novel protein synthesis regulatory nodes into first-in-class precision medicines to treat the most challenging cancers. The company’s vision is to establish itself as a global pioneer in this new research space as it advances breakthrough therapies to benefit cancer patients worldwide.

    Learn more at abio-x.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Singapore

    • Year Invested

      2022

    • Team

  • Amber Therapeutics is developing Amber-UI, a breakthrough adaptive neuromodulation therapy to treat women suffering with mixed urinary incontinence with the hope of transforming the clinical outcome and quality of life of a large untreated population. Amber-UI runs on the Company’s fully implantable Picostim system that targets the pudendal nerve to both stimulate and sense physiological responses. The therapy is configurable to the individual’s need and can respond dynamically to different events, adapting as needed between modes of operation. Amber’s technology platform is highly versatile and can be used to explore other novel therapy applications in both the pelvis and the broader nervous system, demonstrated by the work being carried out by the Company’s academic partnerships. Learn more at www.amber-tx.com.

  • Amphora Medical was a medical device technology company developing minimally invasive products to restore the quality of life of people suffering from Overactive Bladder Syndrome.

  • AmplifyMD is a turnkey specialty access platform connecting the over 3,300 medical institutions with a lack of specialty access – often in rural or small regions of the United States – to a network of leading specialists. The company provides both the clinical team as well as the software to streamline and automate virtual care delivery and billing workflows and integrates seamlessly with hospitals’ existing EHRs. Learn more at www.amplifymd.com.

  • Apellis Pharmaceuticals, Inc. (NASDAQ: APLS) is a clinical-stage biopharmaceutical company focused on the development of novel therapeutic compounds to treat disease through the inhibition of the complement system, at the level of C3, the central protein in the complement cascade. Learn more at www.apellis.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Crestwood, KY

    • Year Invested

      2017

    • Team

  • AppliedVR is a leader in digital therapeutics, pioneering virtual reality-based treatments that address the complexity of chronic pain with a mission to empower patients with the tools to live life, beyond chronic pain. Rooted in cognitive behavioral therapy and mindfulness, AppliedVR’s EaseVRx is the first VR-based prescription therapeutic to receive Breakthrough Device Designation by the FDA.  Learn more at www.appliedvr.io.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2021

    • Team

  • AppsFlyer is a mobile advertising measurement platform that allows app marketers to measure their user acquisition campaigns in real-time. Learn more at www.appsflyer.com.


    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Herzliya, Israel

    • Team

  • Argyle provides a single global access point to employment data. From that access point, any business can process verifications, gain real-time transparency into earnings as well as view and update worker profile details. By removing the barriers between a worker, the companies they make money from, and the business they buy services and products from Argyle has reimagined how employment data can be used. Argyle was founded in 2018 and operates out of New York. Learn more at www.argyle.io.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2020

    • Team

  • The company specializes in personalized full-cycle cancer treatments and management, from prevention and early test of symptoms to the adoption of advanced cancer treatment methods. Learn more at www.arion.care.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Beijing, China

    • Year Invested

      2019

    • Team

  • ARTBIO is a clinical-stage radiopharmaceutical company redefining cancer care by creating a new class of alpha radioligand therapies (ARTs). The unique ARTBIO approach selects the optimal alpha-emitting isotope (Pb212) and tumor-specific targets to create highly targeted therapeutics. The company’s AlphaDirectTM technology, a first-of-its-kind Pb212 isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. Learn more: www.artbiotx.com

  • Artemis Health helps companies utilize their data to optimize their benefits programs while minimizing their spend. The Artemis Platform provides customers with actionable data on their benefits programs, opportunities and gaps, and easy-to-use tools to help them make great decisions. Artemis Health was acquired by Nomi Health in 2022.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Salt Lake City, UT

    • Year Invested

      2017

    • Team

  • Arvelle Therapeutics is a biopharmaceutical company with the mission of bringing innovative solutions to patients suffering from CNS disorders. Arvelle is responsible for the development and commercialization of cenobamate, an investigational antiepileptic drug, in the European market.  Arvelle Therapeutics was acquired by Angelini Pharma in January 2021.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Basel, Switzerland

    • Year Invested

      2019

    • Team

  • Ashby exists to deliver a new standard of recruiting software to enable hiring excellence. It’s all-in-one recruiting platform enables high growth companies to hire more efficiently by combining features for the entire recruiting process, from sourcing to offer, with advanced analytics and automation. Learn more at www.ashbyhq.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2020

    • Team

  • Asymmetry Finance is a groundbreaking DeFi protocol designed to decentralize Ethereum by making complex strategies with market leading yield and asymmetric upside accessible to the next billion Web3 users. Learn more at asymmetry.finance.

  • Atalanta Therapeutics is a biotechnology company pioneering new treatment options for neurodegenerative diseases by utilizing its proprietary RNA interference platform.  Learn more at www.atalantatx.com.

  • Audacy is a space communications service provider delivering continuous connectivity and data in real time to spacecraft operators. With a spectrum license granted by the U.S. Federal Communications Commission (FCC) in June 2018, and by deploying a network of medium Earth orbit relay satellites and ground facilities, Audacy will provide the first commercially available inter-satellite data relay network, enabling seamless low-Earth orbit coverage and always-on connectivity from ground to lunar orbit. To learn more, visit https://audacy.space.

    • Category

      • FrontierTech
    • Status

      • Private
  • Avalyn is a biopharma company committed to developing improved therapies for the treatment of idiopathic pulmonary fibrosis (IPF) and other severe respiratory diseases. Learn more at www.avalynpharma.com.

  • AvantStay delivers exceptional, unique stays for group travelers. The company has built a tech-enabled millennial hospitality brand to be the new standard for group experience.  Unlike typical short-term rentals, Avantstay controls the entire guest experience. This allows the company to ensure the quality of a guest’s stay will be consistent across all homes and to deliver hotel-level comfort in an authentic differentiated setting. Learn more at avantstay.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2018

    • Team

  • AvenCell derives its name from the French word “avenir” to reflect the aim to be the FUTURE of cell therapy. AvenCell is building a truly transformative cell therapy company that targets difficult-to-treat cancers, with its lead programs focusing on acute myeloid leukemia (AML) and additional programs targeting other hematological malignancies. AvenCell was formed with the goal to create truly allogeneic cells that persist as long or longer than autologous therapies and develop a universal and switchable construct that allows complete control and target redirection of T cells after they are infused into a patient. Integration of these two platforms allows for complete separation of the manufacturing of cells from ultimate patient and cancer target, thus providing significant scalability potential at orders of magnitude more efficient than current approaches.

    Learn more at avencell.com.

  • AviadoBio is a pioneering gene therapy company focused on developing and delivering transformative medicines for people living with neurodegenerative disorders. Learn more at www.aviadobio.com.

  • Avidity Biosciences (NASDAQ: RNA)  is a biotech company pioneering a new class of precision medicines – Antibody-siRNA Conjugates (ASC™) – which combine the strengths of monoclonal antibodies and siRNA-based therapeutics to overcome barriers to the delivery of siRNA and target genetic drivers of disease. Learn more at www.aviditybiosciences.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      San Diego, CA

    • Year Invested

      2014

  • Avivomed, is a medical device company developing innovative neuromodulation technology to treat large disease populations.  Learn more at www.avivomed.com.

     

  • Axoni is a New York-based technology firm that specializes in distributed ledger infrastructure with clients that include many of the world’s largest financial institutions and capital markets infrastructure companies. Founded in 2013 by a team of distributed ledger technology experts, the company offers blockchain infrastructure, distributed application development, and workflow automation tools. Learn more at www.axoni.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2016

    • Team

  • b-ONE Ortho Corp. is an emerging orthopedic technology company dedicated to the development of innovative orthopedic healthcare solutions that restore patient mobility and improve surgical outcomes. Every day we are committed to becoming the most credible choice for orthopedic products worldwide.

    Learn more at b1.co.

  • Zhejiang Bang Er Medical Investment Management Co., Ltd. is a leading private medical service provider that operates several private hospitals specializing in orthopedic care and related services in China. Learn more at www.zjbanger.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Zhejiang, China

    • Year Invested

      2015

    • Team

  • Beam Therapeutics (NASDAQ: BEAM) is pioneering the use of CRISPR base editing to develop precision genetic medicines that treat disease, one letter at a time. Learn more at www.beamtx.com.

  • Benchling is the leader in cloud-based informatics for life science R&D. The company offers a unified R&D platform purpose-built for biologics, including solutions for Lab Notebook, Molecular Biology, Bioregistration, Sample Tracking, Requests and Workflow Management. Benchling is used by over 100,000 scientists globally throughout multinational pharmaceutical corporations, emerging biotechnology companies, and major research institutions. Learn more at https://benchling.com/.

    • Category

      • Enterprise IT
      • Health IT/Services
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2018

    • Team

  • BenchSci exponentially increases the speed and quality of life-saving research by empowering scientists with the world’s most advanced biomedical artificial intelligence to run more successful experiments. Learn more at www.benchsci.com.

  • Better Life Medical is a fully-integrated hearing aid manufacturer developing and commercializing novel digital programmable hearing aid solutions for the Chinese market. Learn more at www.goblm.com.cn/.

  • Better Life Partners is a provider of high-quality, integrated medical and behavioral healthcare to people not well served by the traditional system. The company’s offerings include group therapy sessions with a special curriculum that utilizes evidence-based cognitive and dialectical behavioral therapy to build a sense of community and purpose toward a better life, enabling patients of substance abuse to be provided with aid and support to get sober.  Learn more at www.betterlifepartners.com.

     

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Hanover, NH

    • Year Invested

      2021

    • Team

  • Bicara Therapeutics is a clinical-stage biotechnology company developing first-in-class biologics engineered to bring together the precision of targeted therapy and the power of tumor modulators. The company’s bifunctional antibodies are designed to deliver an immunomodulatory payload directly to the tumor microenvironment to ramp up immune cell activity, potentially offering long-lasting efficacy. Learn more at www.bicara.com

  • Bikam Pharmaceuticals is a drug discovery company focused on developing novel therapies for diseases of the eye with exceptionally high unmet medical need. Bikam Pharmaceuticals was acquired by Shire.

     

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Cambridge, MA

    • Year Invested

      2007

    • Team

  • BioConnect Systems was a medical device company that developed a CE-Marked product for improving dialysis access  surgery.

  • BioPalette is a life science start up formed out of Kobe University developing base editing technology for a range of applications. Learn more at www.biopalette.co.jp.

  • BioRegen Biomedical is a fully integrated medical product company based on a proprietary technology platform. BioRegen is developing and commercializing high quality hyaluronic acid (“HA”) based products for the Chinese market. Learn more at www.bioregenmed.com.

    • Category

      • MedTech
    • Status

      • Private
    • Location

      China

    • Year Invested

      2010

    • Team

  • Bison Trails is a blockchain infrastructure platform that was acquired by Coinbase in January 2021. The platform provides a suite of services, including: “Query & Transact”, enabling developers to more easily retrieve and analyze data generated from blockchain networks for trading, research or development purposes, and “Participate,” enabling companies to participate in a blockchains proof of stake (PoS) consensus mechanism and earn newly issued cryptocurrency rewards. These services are integrated into Coinbase Developer Platform and are offered through the Coinbase website. Learn more at www.coinbase.com/developer-platform.

    • Category

      • Crypto
    • Status

      • Acquired
    • Location

      Pearland, TX

    • Year Invested

      2019

    • Team

  • BlackDuck secures and manages open source software worldwide, eliminating open source security vulnerabilities & license compliance pain. BlackDuck was acquired by Synopsys in 2017.  Learn more at www.blackducksoftware.com.

    • Category

      • Enterprise IT
    • Status

      • Acquired
  • Blispay makes financing easy and accessible for merchants and shoppers. The company provides point-of-sale financing with no integration and no additional costs to the merchant, ultimately helping businesses increase sales while providing consumers with better buying options everywhere they shop. Approved shoppers will additionally receive the Blispay credit card and continue to receive no interest, no payments on all purchases over $199 if paid in full in six months, plus automatic 2 percent cash back everywhere Visa is accepted. Located in Baltimore, Blispay’s team includes pioneers of the financing industry with experience that spans banking, credit and retail.  Blispay was acquired by Alliance Data in 2019. Learn more at www.blispay.com.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      Baltimore, MD

    • Year Invested

      2017

  • Blue Rabbit is a chronic disease management platform designed to coordinate diagnostics, medications and nutrition for animal patients. The company enables the effortless administration of healthcare through an ecosystem of technology driven solutions and services. Learn more at www.bluerabbit.vet.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Portland, Maine

    • Year Invested

      2022

    • Team

  • Bluebird Kids Health reimagines pediatric primary care in underserved communities. They’re on a mission to provide exceptional care, so that every child can thrive. Their innovative pediatric value-based care model provides comprehensive, evidence-based care, tailored to the unique needs of each family. They strive for exceptional health outcomes, reduced medical costs, and an unparalleled experience for children, families, and their dedicated care teams.

    Learn more at bluebirdkids.com.

  • Blueprint Medicines (NASDAQ: BPMC) is a precision therapy company striving to improve human health. Learn more at www.blueprintmedicines.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2012

    • Team

  • Buoy is an online symptom and cure checker that uses an intelligent algorithm backed by medical data to diagnose patients. Learn more at www.buoyhealth.com.

  • Burro, formally known as Augean Robotics, is a Philadelphia-based robotics company building an autonomous platform designed to free growers and their workforce from tedious tasks, while building the modular base for greater autonomy. Founded in 2017, the company offers the only fully autonomous, plug-and-play collaborative farming robot on the market. To learn more Burro, visit burro.ai.

  • Cadence Neuroscience is a medical device company developing new therapies for the treatment of epilepsy and other neurological disorders. The company’s core technology was developed at Mayo Clinic and is under clinical evaluation. Founded in 2017 and headquartered in Redmond, Washington, Cadence is led by seasoned executives with extensive backgrounds in neural implant product development and clinical studies. Learn more: https://www.cadenceneuro.com/

  • Canary Technologies is modernizing the hotel tech stack, with the first mobile web end-to-end Guest Management System, digitizing everything from post-booking through checkout. Trusted by thousands of hotels in more than 65 countries, including Four Seasons, Choice Hotels, Standard Hotels and Ace Hotel Group, Canary’s solutions help hotels eliminate paper processes, boost revenue with upsells, raise staff efficiency, ensure PCI compliance, improve the guest experience, and reduce chargebacks and payment fraud. Learn more at canarytechnologies.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2020

    • Team

  • Canoe’s mission is to unlock efficiencies in alternative investment processes by introducing purpose-built automation into the workflows of institutional investors, asset servicers, capital allocators and wealth managers. Learn more at canoeintelligence.com.

  • Capital Rx is built around the mission of changing the way prescription drugs are priced and patients are serviced. A health technology company daring to reimagine the healthcare industry, Capital Rx is executing on that mission with its enterprise pharmacy platform JUDI™, which connects every aspect of the pharmacy ecosystem in one platform, enabling patient engagement and increasing efficiency to achieve the highest standards of clinical care. Learn more at www.cap-rx.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2022

    • Team

  • Caplin Point Laboratories Limited is a fast growing pharmaceutical company with a unique business model catering predominantly to emerging markets of Latin America and Africa. Caplin Point Laboratories Limited has state of the art manufacturing facilities that cater to a complete range of finished dosage forms. The Company has also entered regulated markets such as US through its Wholly Owned Subsidiary Caplin Steriles Limited. Learn more at www.caplinpoint.net.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Chennai, Tamil Nadu, India

    • Year Invested

      2019

    • Team

  • CardioKine is a pharmaceutical company focused on the development of lixivaptan, an oral compound under development for the potential treatment of hyponatremia in patients with congestive heart failure. CardioKine was acquired by Cornerstone Therapeutics.

  • CareStack™ is a cloud based platform that combines dental practice management, patient engagement and data analytics. Learn more at www.carestack.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Orlando, Florida and Kerela, India

    • Year Invested

      2018

    • Team

  • Caribou (NASDAQ:CRBU) is a leading company in CRISPR genome editing founded by pioneers of CRISPR-Cas9 biology. Caribou’s proprietary technologies put the company at the forefront of the development of new medical therapies. Learn more at www.cariboubio.com.

  • Carrot Fertility is a global fertility benefits provider for employers, built to support employees through their entire fertility healthcare journey. Companies use Carrot to customize a fertility benefit that provides employees financial, medical, and emotional support as they pursue parenthood, resulting in better clinical outcomes. Carrot’s program includes egg freezing, in vitro fertilization (IVF), adoption, donor and gestational carrier services; Carrot Rx, a premium pharmacy experience, at significant savings; Carrot Pregnancy; and the Carrot Card®, a flexible fertility benefits debit card employees can use to pay for their care. Learn more at www.get-carrot.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2020

    • Team

  • Casa is the secure home for your Bitcoin. The Company builds tools at the forefront of Bitcoin self-custody, enabling individuals to take control of their wealth by holding their own Bitcoin private keys in an easy and secure manner. Casa is building for a future where self-custody is default and every individual, family, and business can freely manage their own wealth and data. Learn more at casa.io.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Denver, CO

    • Year Invested

      2021

    • Team

  • Castle is the security industry’s first zero-configuration solution for account takeover (ATO) protection. Learn more at www.castle.io.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2016

    • Team

  • Castor is a leading provider of decentralized and hybrid clinical trial solutions to democratize research. With the highest rated eClinical platform for decentralized and hybrid clinical trials, Castor’s plug and play platform offers rapid deployment at scale, enabling researchers to create a trial in a matter of clicks, with easy enrollment, consent and real-world data capture. Learn more at www.castoredc.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Amsterdam, The Netherlands and Hoboken, NJ

    • Year Invested

      2021

    • Team

  • Centivo is a new type of self-funded health plan built specifically for employers and their employees and families.  The Company targets zero healthcare trend and improved healthcare outcomes by rewarding members and providers for smart choices and actions while delivering an exceptional member experience. Centivo serves as a health plan or third-party administrator (TPA) for employers and partners closely with local health plans and TPAs to enhance their offerings. Learn more at www.centivo.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2018

    • Team

  • Chaos Labs leads the blockchain risk management industry with innovative solutions for the evolving onchain financial landscape. The company’s Risk Platform provides comprehensive economic security for crypto protocols through advanced monitoring, real-time simulations, and cutting-edge Risk Oracles. Chaos Labs enables protocols to verify stability across all market conditions, merging offchain observability with onchain risk parameter adjustments. This empowers DeFi applications to adapt instantly to market volatility, allowing teams to monitor health, execute proactive changes, protect user funds, and optimize capital efficiency. Learn more at chaoslabs.xyz.

  • CHARM Therapeutics is a 3D deep-learning research Company discovering and developing transformational medicines. Based on the award-winning discoveries of David Baker in protein-folding, CHARM has developed a proprietary technology based on the first rapid, accurate protein/ligand co-folding algorithm. The Company’s mission is to use these insights to address challenging targets in cancer and other disease areas and discover and develop new drugs against these targets. Learn more at www.charmtx.com.

     

  • Checkmate Pharmaceuticals (NASDAQ: CMPI) is a clinical stage company pursuing a novel approach to specifically activating the innate and adaptive arms of the immune system to recognize and ultimately destroy tumor cells. Checkmate Pharmaceuticals was acquired by Regeneron (NASDAQ:REGH) in 2022.

    • Category

      • Therapeutics
    • Status

      • Acquired
      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2017

    • Team

  • Cipla Health focuses on developing and commercializing products in the consumer healthcare and over-the-counter categories. Learn more at www.ciplahealth.in.

  • Cloudant offered a distributed NoSQL database-as-a-service (DBaaS) for developers creating web and mobile applications. Cloudant was acquired by IBM in 2014.

  • CLST (pronounced “Caeleste”) is the institutional communications venue to lend or borrow stablecoins and crypto assets, automating multi-dealer price negotiation and price matching for institutional lenders. CLST Markets integrates next generation features such as automated collateral management, counterparty risk assessments, interest rate benchmarking, blockchain-based electronic promissory notes and wallet connectivity for automated settlements. CLST aims to resolve market uncertainties and scaling issues in uncollateralized and collateralized lending and borrowing of stablecoins and crypto assets. Learn more at www.clst.com.

  • Codeship operates a cloud-based platform that helps software developers test and deploy their code more efficiently through continuous integration (CI) and continuous deployment (CD). Codeship was acquired by Cloudbees in 2018. Learn more at codeship.com.

  • Cogent Biosciences (NASDAQ:COGT) (formerly Unum Therapeutics) has built an antibody-coupled T-cell receptor (ACTR) platform that, when combined with tumor-specific antibodies, directs an individual’s cytotoxic T-lymphocytes (CTLs) to kill tumor cells. Learn more at www.cogentbio.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2014

  • Coherus Biosciences (NASDAQ: CHRS) is a biosimilar-focused, biologics platform company with the cutting-edge analytics, process science, and clinical and regulatory capabilities to develop and commercialize high-quality biosimilar therapeutics worldwide. Learn more at www.coherus.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Redwood City, CA

    • Year Invested

      2014

  • Coin Metrics is the leading provider of crypto financial intelligence, offering network data, market data, indexes and network risk solutions to the most prestigious institutions touching cryptoassets. Coin Metrics was founded in 2017 as an open-source project to determine the economic significance of public blockchains. Today, they expand on that original purpose to empower people and institutions to make informed crypto financial decisions. Coin Metrics aim to usher the world’s premier financial institutions into crypto with the most trusted data and insights. Learn more at www.coinmetrics.io.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2019

    • Team

  • Coincover provides a complete blockchain protection solution, addressing the most significant barrier to mainstream adoption: trust. Thier protection solutions ensure that access and assets are never lost. Today, Coincover helps over 350 of the biggest names in blockchain, including Fireblocks, BitGo, and Ledger, protect themselves and their customers from theft, hacking, and human error. Learn more at www.coincover.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Wales, UK

    • Year Invested

      2021

    • Team

  • Comanche Biopharma is a maternal and fetal medicine biopharmaceutical company working to lower the risks of pregnancy and premature births worldwide. We are currently developing the world’s first treatment for preeclampsia, which affects more than 10 million women every year. Learn more at www.comanchebiopharma.com.

  • Compass Therapeutics (NASDAQ: CMPX) is comprehensively drugging the tumor-immune synapse with human antibodies against over 50 cell surface and soluble targets. Learn more at www.compasstherapeutics.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2015

    • Team

  • ConnexPay is revolutionizing the payment distribution process by offering a combined merchant acquiring and virtual card issuing solution for mid-sized companies. The company’s technology simplifies an antiquated workflow, eliminates the need for pre-funded accounts, reduces supplier risk and the cost of accepting card payments while safeguarding consumer spend. Backed by  F-Prime Capital and BIP Capital, ConnexPay is becoming the industry leader in payments for industries historically viewed as high risk to payment providers.  Learn more at www.connexpay.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Atlanta, GA

    • Year Invested

      2020

    • Team

  • CORE provides high-end diagnostics services for disease stratification and therapy selection. Learn more at www.corediagnostics.in.

  • Cúram Software was a leading provider of solutions for social program management organizations. Cúram Software solutions helped leaders innovate across services and organizations to meet and exceed citizen expectations and support improved outcomes. The company was acquired by IBM in 2011.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Dublin, Ireland

  • Curegenix is a Chinese leader in discovery and development of novel drugs in stem cell related diseases. Learn more at www.curegenix.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      China

    • Year Invested

      2016

    • Team

  • Curie.Bio is a founder-focused seed-stage venture firm combined with an industry-grade therapeutics accelerator focused on one thing: helping entrepreneurial founders launch viable therapeutics companies. Curie.Bio does this by giving founders access to a team of the world’s best drug hunters and drug makers, seed capital, and best-of-breed services – everything a founder needs to get from concept to a compelling quality dataset that enables an awesome Series A financing. In a nutshell, we want founders in control of their own company and focused on their area of expertise and creativity, while we help make the rest happen smoothly. Learn more at Curie.Bio.

  • Cytek Biosciences Inc.  (NASDAQ: CTBK) is a leading flow cytometry solution provider that provides compact, affordable instruments with high multiplexing capabilities. Learn more at www.cytekbio.com.

    • Category

      • MedTech
    • Status

      • Public
    • Location

      China

    • Year Invested

      2015

    • Team

  • Deal Engine is a Miami-based travel software company, with a mission to bring digital transformation to the travel industry. Utilizing proprietary AI and APIs, Deal Engine brings automation to travel, eliminating manual processes, and making sure people spend their time where they generate more value. Learn more at deal-engine.com.

  • Denali Therapeutics (NASDAQ:DNLI) is dedicated to defeating neurodegenerative diseases through rigorous therapeutic discovery and development. Learn more at www.denalitherapeutics.com.

  • Devoted Health is building a tech-enabled health insurance and clinical services solution focused on dramatically improving health care for seniors in the U.S. Learn more at www.devoted.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Waltham, MA

    • Year Invested

      2017

    • Team

  • Digital Assets Data is a financial technology and data company building enterprise-grade software and data feeds for crypto hedge funds, family offices, research firms, global consulting firms, banks, sovereigns, and other market participants. Digital Assets Data was acquired by NYDIG, a leading provider of investment and technology solutions for Bitcoin, in January 2021. Learn more at www.digitalassetsdata.com.

    • Category

      • Crypto
    • Status

      • Acquired
    • Location

      Denver, CO

    • Year Invested

      2019

    • Team

  • Dimension Therapeutics was a leader in the development of AAV (adeno-associated virus) gene therapies for rare disease. Dimension Therapeutics was acquired by Ultragenyx Pharmaceuticals (NASDAQ:RARE).

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Cambridge, MA

    • Year Invested

      2013

    • Team

  • Dinari is a real-world asset tokenization platform and distribution network focused on bringing US stocks to international and underserved markets using blockchain rails in a cheap, accessible, and secure manner. Learn more at dinari.com.

  • Dispatch is wealthtech’s first data orchestration company. Its mission is simple: to seamlessly sync client data across the advisor’s tech stack and to free wealthtech companies from the burden of continually building and maintaining integrations. Learn more at dispatch.io

  • Doceree is the first global network of HCP-only platforms for programmatic messaging. Doceree facilitates messaging between life sciences brands and healthcare professionals (HCPs) through an extensive global network of digital endemic and point-of-care platforms to programmatically deliver at scale accurate and transparent messages to HCPs. Learn more at www.doceree.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Parsippany, NJ

    • Year Invested

      2022

    • Team

  • DUST Identity is a leading authentication and anchored digital thread solution for real-world objects that connects data to physical things. DUST Identity’s award-winning anchored digital thread solution delivers the ability to track and trace an object’s pedigree and provenance throughout its lifecycle – providing access to the right information at the right place and time. Learn more at www.dustidentity.com.

  • Eaglebrook is a crypto investment platform that provides RIAs with direct access to bitcoin and digital assets. The firm operates one of the largest SMA Platforms in the crypto market. Eaglebrook’s investment platform offers access to tax optimized Bitcoin and Ethereum separately managed accounts (SMAs) and third-party investment manager strategies held at an institutional qualified custodian. Learn more at www.eaglebrook.com.

  • Elementus helps solve the toughest blockchain data problems so organizations can navigate web3 safely and with confidence. Its intelligence platform is used by financial institutions to build the future of finance and commerce on the bedrock of blockchain, and by key U.S. governmental agencies to solve some of the most high-profile ransomware investigations. Elementus helps organizations investigate on-chain activities, identify risk, discover valuable market intelligence or a combination of all three. By providing a complete view into flows of funds at the most granular level, Elementus delivers actionable insights and transparency needed to grow and prosper safely in a web3 world. Learn more at elementus.io.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2019

    • Team

  • Eleos is pioneering CareOps Automation. By consolidating the entire behavioral care workflow — everything from progress notes all the way to session intelligence— clinicians are freed from time-consuming operational burdens. Eleos takes care of CareOps, honing in on automating operational necessities, including all documentation, compliance administration as well as providing deep clinical insights through session intelligence. Eleos makes evidence-based behavioral care a reality so clinicians, providers, and networks can measurably and comparatively track treatment and progress. Learn more at eleos.health.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Boston, MA and Tel Aviv, Israel

    • Year Invested

      2022

    • Team

  • Elucidata was founded in 2015 by University of Chicago and MIT graduate Dr. Abhishek Jha and IIT Delhi alumnus Swetabh Pathak. The company’s cutting-edge platform Polly operates on unique Bio-NLP technology that cleans and links 26+ R&D data types and caters to companies in various stages of their drug discovery process. The platform helps data science teams scale by providing them 70 TB of ML-Ready biomedical data, from ~30 public and proprietary sources. Today, 3 of the top 10 pharmaceutical companies are using Polly to fast track their R&D initiatives. Learn more at www.elucidata.io.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Cambridge, MA

    • Year Invested

      2022

    • Team

  • Embark Veterinary, Inc. launched in 2015 with a mission to end preventable disease in dogs. An Embark Dog DNA Test enables pet owners to learn about their dog’s breed, ancestry, health, and what diseases may be in the future – all with a simple cheek swab. By using 100 times more genetic information than any other test available, the company offers the most accurate results on the market. Embark was started by two brothers, Adam and Ryan Boyko, who have a passion for scientific research and a lifelong love of dogs. Embark is an official research partner with Cornell University College of Veterinary Medicine.  Learn more at www.embarkvet.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2019

    • Team

  • Engrail Therapeutics is a clinical-stage pharmaceutical company with the aspiration of becoming a leader in neuroscience. Their purpose is to deliver transformational therapies that improve the lives of patients with neuropsychiatric and neurodevelopmental diseases.
    Learn more at www.engrail.com.

  • Ensoma is expanding the reach of the curative power of genomic medicine by pioneering a next-generation in vivo approach using its Engenious™ vectors. Ensoma’s vectors are designed to deliver a diverse range of gene modification technologies without the need for stem cell collection or prior myeloablative conditioning (e.g. chemotherapy). Learn more at www.ensoma.com.

  • Enzene is an innovation-driven biotech company a subsidiary of Alkem Laboratories Ltd. (one of the top five pharmaceutical companies in India*) located in Pune, India. Enzene’s focus lies in producing biosimilars, novel biologics, synthetic peptides and phytopharmaceuticals. Enzene also offers a range of biologics CDMO and CMO services with capabilities from clone development up to GMP manufacturing supported by bio-reactor capacities ranging from 20 litres to 2000 litres.

    Learn more at enzene.com.

  • Equip delivers modern eating disorder treatment through family-based care that promises lasting recovery at home. Created by experts in the field and people who’ve been there, Equip provides each patient with a five-person dedicated care team including a therapist, dietician, physician, and peer & family mentor. Learn more at www.equip.health.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      San Diego, CA

    • Year Invested

      2019

    • Team

  • Eris Exchange is an interest rate swaps trading venue that provides the flexibility of OTC swaps within a futures contract, helping institutions manage the complexities of Dodd Frank derivatives regulations. Learn more at www.erisfutures.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Chicago, IL

    • Year Invested

      2012

    • Team

  • Ethena is a digital finance company focused on providing innovative solutions within the cryptocurrency and blockchain sectors. The company offers services such as developing and managing stablecoins, which are cryptocurrencies pegged to traditional assets like the US dollar to minimize price volatility. Additionally, Ethena operates in the decentralized finance (DeFi) space, enabling users to participate in financial activities like lending, borrowing, and trading without traditional intermediaries through the use of smart contracts on blockchain networks. Ethena also provides tools for managing digital assets, helping users securely store, transfer, and utilize their cryptocurrencies with services like wallets and investment products. The company is committed to leveraging blockchain technology for its transparency, security, and efficiency, aiming to bridge the gap between traditional finance and the digital economy. Through these efforts, Ethena makes it easier for individuals and businesses to adopt and benefit from cryptocurrency technologies. Learn more at ethena.fi.

  • Through the synergies of cross-disciplinary collaboration and technological innovation, EurekaBio has consistently pushed the boundaries of therapy. EurekaBio has brought forth advanced cellular drug production solutions and the EuLV™ lentiviral vector platform. These breakthroughs, including high-titer stable lentiviral vector packaging and producer cell lines, are poised to play a pivotal role in the global commercialization of CGT drugs. Our ultimate aim is to bring tangible benefits to patients worldwide by ushering in a new era of advanced and accessible therapies. Learn more: https://www.eurekabio.com/

  • Even Financial is an NYC based FinTech company focused on evolving how financial institutions connect with consumers and provide them with the best product recommendations at the right moment, facilitating an on-demand and personalized customer acquisition experience across the entire financial services ecosystem. The Even platform serves as a trusted intermediary for financial institutions – including Prosper, Lending Club and Marcus by Goldman Sachs – that helps find consumers and distribute their products digitally. Even’s industry-leading search, comparison and recommendation API is an infrastructure layer that enables hundreds of diverse partners – including Credit.com, Transunion, Money Under 30, Credit Sesame and The Penny Hoarder – to power comprehensive personal finance websites, mobile apps and other offerings with a modern platform that is proven to accelerate customer acquisition through optimal product recommendations, lowering cost of acquisition and maximizing monetization. Even Financial was acquired by MoneyLion in 2021.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      New York, NY

    • Year Invested

      2015

    • Team

  • Expressable is a virtual speech therapy provider committed to expanding access to quality services for everyone in need. Expressable has pioneered a family-centered and research-based care model that uses technology and education to integrate speech therapy techniques into children’s daily lives, improving outcomes and experiences. Learn more at www.expressable.io.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Austin, TX

    • Year Invested

      2021

    • Team

  • Eyebright Medical Technology Co., Ltd. (SHA: 688050) is an emerging leader in the ophthalmologic device market in China. Learn more at www.ebmedical.com.

    • Category

      • MedTech
    • Status

      • Public
    • Location

      Beijing, China

    • Year Invested

      2015

    • Team

  • Eywa is a global generic pharmaceutical company engaged in research and development, manufacture, marketing, sale, and distribution of generic finished dosage formulations. Learn more at www.eywapharma.com.

  • FalconX is a digital asset trading platform that provides clients best execution using data science. FalconX has offices in Silicon Valley, Chicago, Bengaluru, and Malta. Learn more at falconx.io.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      San Mateo, CA

    • Year Invested

      2019

    • Team

  • Farapulse is a medical device company developing a novel approach to treating a range of arrhythmias using pulsed electric field. Farapulse was acquired by Boston Scientific in 2021.

  • FCB Health is a health insurance and services company that aims to resolve the longstanding financial burden of rising medical expenses in rural China. FCB Health was acquired by Interpublic Group (IPG).

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Jiangsu, China

    • Year Invested

      2019

    • Team

  • Figment’s purpose is to build a better Internet by increasing usage of the next generation of Proof of Stake blockchains. These efficient blockchains give people greater control of their data, more privacy, and increase financial inclusion. By eliminating intermediaries they also limit the power of centralized data monopolies, rent seeking institutions and anti-social algorithms. Learn more at figment.io.

  • Founded by experienced physician innovators and technology entrepreneurs, Firefly marries sophisticated technology with a thoughtful care team experience for continuous, intelligent care that changes behavior and drives value. The platform enables people to make smart choices about their health, while allowing clinicians to provide unparalleled, consistent and proactive care. Learn more at firefly.health.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Wellesley, MA

    • Year Invested

      2019

    • Team

  • Flipside Crypto provides business intelligence to crypto organizations. Their suite of analytics tools provides insights into user behaviors, developer activities, and financial health. Flipside also rates cryptocurrencies utilizing, FCAS, a relative value for measuring the fundamental health of cryptocurrency ecosystems. Learn more at flipsidecrypto.xyz.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2019

    • Team

  • Flywire (NASDAQ:FLYW) solves complex payment problems for businesses and institutions to empower new opportunities globally and locally. Its full-service billing, payment and receivables solutions connect all the entities involved to make those transactions faster, more secure, less expensive, and more transparent. Clients in a variety of industry verticals use Flywire’s platform to tailor the payment experience for their customers and to create a single point of visibility and control for payer engagement and receivables management – from invoicing and payment through reconciliation. Learn more at www.flywire.com.

    • Category

      • FinTech
    • Status

      • Public
    • Location

      Boston, MA

    • Year Invested

      2013

    • Team

  • FoldRx Pharmaceuticals focuses on creating disease modifying drug therapies for diseases of protein misfolding. FoldRx developed, tafamidis, the first-in-class therapy approved or TTR amyloidosis. FoldRx was acquired by Pfizer.

  • Funnel’s product is a Data Core used by 800 forward-thinking organizations across a wide set of industry verticals to automatically import marketing data and make it Business-Ready. The Swedish Software-as-a-Service (SaaS) company was founded by Fredrik Skantze and Per Made in 2014. Funnel has 140 employees and offices in Stockholm and Boston. Learn more at funnel.io.

  • FutureAdvisor is an online Registered Investment Advisor (RIA) that provides mass affluent investors with low cost, personalized portfolios through an easy-to-use and intuitive user experience. FutureAdvisor was acquired by BlackRock in 2015.  Learn more at www.futureadvisor.com.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      San Francisco, CA

    • Year Invested

      2014

    • Team

  • Galatea Bio is a biobank intended to improve diagnostic testing and accelerate drug discovery in diverse underserved populations. The company functions as a biosample to bioinformatics platform for powering genomic discovery in understudied populations and identifies patients at risk of suffering severe multi-inflammatory syndromes or infections.  Learn more at www.galatea.bio.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Hialeah, FL

    • Year Invested

      2021

    • Team

  • Genomics plc’s vision is to use genomic insights to transform the drug discovery industry by getting better drugs developed more quickly and targeted at the right group of patients. Learn more at https://www.genomicsplc.com

  • GeoTel is a producer of call-routing telecommunications software. GeoTel was acquired by Cisco in 1999. Learn more about GeoTel at www.geo-tel.com.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Lowell, MA

  • GoodData is the first company to offer a complete business intelligence platform-as-a-service, providing customers and partners operational dashboards, advanced reporting and data warehousing at a fraction of the cost and complexity of other approaches. Learn more at www.gooddata.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA & Prague, Czech Republic

  • Grove provides node infrastructure services for applications, enterprises, and users to interact with blockchains. At its core, Grove is a RPC (Remote Procedure Call) service that enables users to read and write data to over 40 blockchains. Grove is built on top of the Pocket Network, a global, decentralized network of nodes. Through their portal, Grove provides a performance layer that enhances the reliability and scalability of Pocket while also ensuring the high quality service users demand. Learn more at grove.city.

  • Gu Sheng Tang (“GST”) is a Guangzhou, China-based healthcare services provider that operates a chain of private clinics specializing in traditional Chinese medicine. Learn more at www.gstzy.cn.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Guangzhou, China

    • Year Invested

      2015

    • Team

  • Guros is a digital insurance marketplace in Mexico that’s transforming the entire insurance experience, from purchasing to managing vehicle insurance. We’re on a mission to democratize insurance in Latin America; both for end-customers and neobanks/fintechs who want to embed insurance into their platform, but need to do so in a much simpler, faster, and reliable way. Learn more at www.guros.com.

  • Gyenno is a digital health company based in Shenzhen, China that is developing a holistic specialty care platform to improve diagnosis, disease management, and clinical research in Parkinson’s Disease and other CNS disorders. Lean more at www.gyenno.com/index-en.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Shenzhen, China

    • Year Invested

      2021

    • Team

  • Health Technology is a mobile platform for hospitals that connects patients, optimizes the patient’s hospital visit experience, and streamlines administrator workflow. Learn more at www.gzhc365.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Guangzhou, China

    • Year Invested

      2016

    • Team

  • HiLabs is a leading provider of AI-powered solutions to clean dirty data, unlocking its hidden potential for healthcare transformation. HiLabs is committed to transforming the healthcare industry through innovation, collaboration, and a relentless focus on improving patient outcomes. Learn more at www.hilabs.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Bethesda, Maryland

    • Year Invested

      2024

    • Team

  • Hile (603718.SS) is a leading animal vaccine manufacturer that specializes in sales, marketing and commercialization of animal vaccine products in China. Learn more at www.hile-bio.com/.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Shanghai, China

    • Year Invested

      2010

  • Hone is a Live Learning Platform for organizations to teach transformational leadership, management, and people skills at scale. The company empowers HR and Learning & Development teams to tackle people development in a modern way, with easy deployment of small-group, live cohort learning at scale, and data and tools to measure its impact. Through a blend of live online cohort-based programs, world-class instructors, and a powerful behavior change platform, Hone cultivates soft skills with hard data, leading to lasting behavior change in 90% of learners who go through our programs. Hone has trained thousands of learners in 58+ countries, and serves a rapidly expanding list of clients including GoFundMe, ServiceNow, Rover, Grove Collaborative and more. For more information, visit www.honehq.com.

  • Hoseki builds financial plumbing for the bitcoin-native economy that allows investors to verify and use their holdings in ways that were previously inaccessible. By empowering bitcoin holders with a standardized proof-of-assets service, Hoseki will unleash the bitcoin economy to be larger and more active than ever. Learn more at hoseki.app.

  • Huan Qui Li Kang Technology Co., Ltd. (“HQ”) is an early stage hemostatic product manufacturer in China.

  • Hua Medicine (2552.KHK) is a leading clinical-stage, innovative drug development company in China, focused on novel therapies for the treatment of diabetes and CNS disorders. Learn more at www.huamedicine.com.

  • Icertis, the leading enterprise contract management platform in the cloud, solves the hardest contract management problems on the easiest to use platform. With Icertis, companies accelerate their business by increasing contract velocity, protect against risk by ensuring regulatory and policy compliance, and optimize their commercial relationships by maximizing revenue and reducing costs. Learn more at www.icertis.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Bellevue, WA

    • Year Invested

      2015

  • Iglu is a Brazil-based mobile point-of-sale (PoS) software with native omnichannel capabilities for retailers with omnipresence. It offers retailers an Apple-Store-like delightful product by (1) replacing bulky in-store equipment with a mobile PoS, (2) stitching together disconnected tools such as payments, e-commerce platforms, ERP etc., and (3) integrating with all major credit, debit cards, alternative payment methods such as installment, and the rising real-time payment system in Brazil — PIX. Learn more at https://www.iglu.com.br/

  • Ikano Therapeutics is a specialty pharmaceutical company focused on developing Midazolam Nasal Spray (USL261) for acute repetitive seizures.  Ikano was acquired by UCB.

  • Immuneel is a pioneering clinical stage start-up company leading the change in cell & gene therapies & personalized immunotherapy for patients in India. Headquartered in Bengaluru, Karnataka, India, Immuneel is a research-led, fully integrated cell & gene therapies company committed to bringing breakthrough cancer treatments to India, affordably & build a portfolio of next generation cell therapies. Learn more at www.immuneel.com.

     

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Bangaluru, India

    • Year Invested

      2019

    • Team

  • Indalo Therapeutics, a preclinical biotechnology company dedicated to developing therapies for fibrosis, is formed with an experienced team, strong IP, and robust portfolio of drug candidates.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      St. Louis, MO

    • Year Invested

      2017

    • Team

  • Innovent Biologics (1801.HK) has built a robust pipeline of innovative and commercially promising monoclonal antibodies and other biologics in the fields of oncology, ophthalmology, autoimmune, and cardiovascular diseases. Learn more at www.innoventbio.com.

  • Insilico specializes in artificial intelligence for drug discovery, biomarker development and aging research. Learn more at www.insilico.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Hong Kong

    • Year Invested

      2019

    • Team

  • Intuition provides decentralized infrastructure, developer tools, and applications enabling the creation of an open, flexible knowledge graph enhancing the quality and availability of social knowledge. Learn more at intuition.systems.

  • Invetx is a pioneer in creating novel, protein-based animal health therapeutics to transform standards of care in veterinary medicine. The company leverages a best-in-class, fully integrated biotechnology platform for the discovery, development, and manufacturing of veterinary monoclonal antibodies, and is developing a diverse product pipeline addressing chronic and severe diseases in the veterinary species. In July 2024, Invetx was acquired by Dechra Pharmaceuticals Limited (Dechra), a global specialist veterinary pharmaceuticals business. Learn more at www.invetx.com.

  • Iora Health is building a different kind of health system to deliver high impact, relationship based care. Iora Health was acquired by One Medical in September 2021.

  • Ironwood Pharmaceuticals (NASDAQ:IRWD) developed  linaclotide, a first-in-class therapy that received FDA approval for both irritable bowel syndrome and chronic constipation. Learn more at www.ironwoodpharma.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2002

    • Team

  • Ivenix is dedicated to eliminating infusion-related patient harm, uniquely positioned at the crossroads of healthcare IT and infusion delivery. Ivenix was acquired by Fresenius Kabi in 2022.

  • J-Pharma is a clinical stage biopharmaceutical company with a mission to create and develop novel pharmaceuticals. J-Pharma is conducting trials in Japan for advanced stage cancer patients. Learn more at j-pharma.com.

  • K36 Therapeutics was established with the mission to translate epigenetic modulation of oncogenic pathways into first-in-class small molecule therapies. Its vision is to create breakthrough therapies for the unmet medical needs of cancer patients worldwide. Learn more at https://www.k36tx.com/.

  • Kensho is a cloud-based financial data platform for event-driven and macro analysis, targeting buy-side and sell-side financial professionals that need to quickly and efficiently backtest new trading ideas. Kensho was acquired by S&P Global in 2018 for $550M.  Learn more at www.kensho.com.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      Cambridge, MA

    • Year Invested

      2013

    • Team

  • Kiln is the leading enterprise-grade staking platform, enabling institutional customers to stake assets, and to whitelabel staking functionality into their offering. Kiln runs validators on all major PoS blockchains, with over $4b of crypto assets being programmatically staked and over 4% of the Ethereum network, running on a multi-cloud, multi-region infrastructure. Kiln also provides a validator-agnostic suite of products for fully automated deployment of validators, reporting and commission management, enabling custodians, wallets and exchanges to streamline staking operations across providers. Kiln is SOC2 Type 2 certified. Learn more at www.kiln.fi.

  • Kintsu is at the forefront of DeFi innovation, offering next-generation liquid staking infra that provides enhanced liquidity and security through composable staking rewards. Built on the Monad network, Kintsu’s platform is designed to cater to the evolving needs of the digital asset ecosystem, ensuring a seamless and potentially rewarding staking experience for users. Learn more at kintsu.xyz.

  • KnowYourself is a digital health company that is focused on promoting mental wellness in China.

    Learn more at knowyourself.cc.

  • Kyruus uses the science of data-driven clinical matching to ensure that patients are being matched to the right provider and enabling healthcare systems to coordinate care delivery across their provider networks. Learn more at www.kyruus.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2012

    • Team

  • LakeShore Biopharma (NASDAQ:LSB), formerly YS Biopharma, is a global biopharmaceutical company dedicated to discovering, developing, manufacturing, and commercializing new generations of vaccines and therapeutic biologics for infectious diseases and cancer.

    Learn more at lakeshorebio.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Beijing, China

    • Year Invested

      2012

    • Team

  • Latchel is an award winning property management technology company that empowers property managers to provide unbeatable customer experience with streamlined maintenance operations, and top-tier resident amenities. With built in layers that elevate the resident experience, property managers are also able to increase their revenue by implementing the service as a resident paid amenity. Renters get better service levels that average a 4.8/5 star rating, and property managers can increase both operational efficiency and overall profitability. Learn more at www.latchel.com

  • Laurus Labs (NSE:LAURUSLABS) is a leading manufacturer of Active Pharmaceutical Ingredients (API) for anti-retroviral (HIV-AIDS), oncology, nutraceutical and several other products, with a customer base that spans top-tier generic pharmaceutical companies in India and abroad. Learn more at www.lauruslabs.com.

  • LenoMed is a company that develops and produces insulin pumps.  Learn more at www.lenomed.com.cn.

    • Category

      • MedTech
    • Status

      • Private
    • Location

      Shanghai, China

    • Year Invested

      2018

    • Team

  • Leyden Labs platform targets commonalities of viral families to protect humanity from known and future viruses. Learn more at www.leydenlabs.com.

  • Liazon is a provider of web-based private benefits exchanges to small and medium-sized businesses. Liazon was acquired by Towers Watson in 2013. Learn more at www.liazon.com.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Buffalo, NY

    • Year Invested

      2012

    • Team

  • Lighthouse (formerly OTA Insight) is the leading commercial platform for the travel & hospitality industry. We transform complexity into confidence by providing actionable market insights, business intelligence, and pricing tools that maximize revenue growth. We continually innovate to deliver the best platform for hospitality professionals to price more effectively, measure performance more efficiently, and understand the market in new ways. Trusted by over 65,000 hotels in 185 countries, Lighthouse is the only solution that provides real-time hotel and short-term rental data in a single platform. We strive to deliver the best possible experience with unmatched customer service. We consider our clients as true partners—their success is our success. Learn more at mylighthouse.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      London, England, UK

    • Year Invested

      2017

    • Team

  • LigoCyte Pharmaceuticals was a vaccine discovery and development company with a first-in-class vaccine for norovirus, a pathogen that is a leading cause of viral gastroenteritis (stomach flu). LigoCyte Pharmaceuticals was acquired by Takeda.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Bozeman, MT

    • Year Invested

      2008

    • Team

  • Logixboard is the digital partner for freight forwarders to succeed in today’s highly competitive market. Our web-based platform empowers freight forwarders to do their work more efficiently, increasing customer satisfaction, and unlock the power of their data. Logixboard is a recent graduate of Techstars and is based in Seattle with offices in Bogota, Colombia.  For more information, visit www.logixboard.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Seattle, WA

    • Year Invested

      2019

    • Team

  • Lumere (formerly Procured Health) is an organization comprised of clinicians, researchers, pharmacists and strategic thought leaders focused on helping health systems eliminate unwarranted clinical variation and cut unnecessary costs—specifically related to device and drug selection and utilization. This company was acquired by Global Healthcare Exchange (GHX) in 2020.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Chicago, IL

    • Year Invested

      2012

    • Team

  • Madaket automates the manual, error-prone process of enrollment for healthcare providers and payers. The result is less paperwork and faster payments for hospitals, health systems, and private practices. Learn more at www.madakethealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Cambridge, MA

  • Manthan is a leading cloud analytics company for consumer facing businesses. Their analytics solutions are powered by AI, cloud and prescriptive capabilities. They are unique in their ability to use machine intelligence to process every decision context and respond automatically with actions and recommendations to manage every aspect of a consumer business, whether its marketing, merchandising, channel/store, demand or supply.  Learn more at www.manthan.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Bangalore, India

    • Year Invested

      2009

  • Mathison is the world’s first DEI Operating System. Its end-to-end platform transforms organizations’ hiring and retention strategies to increase diversity with a single place to build their DEI action plan, measure growth and mobilize every team with education and tools. A leader in DEI innovation and research, their book, Hiring for Diversity, was named a bestseller and is referenced by organizations across the globe. Mathison works with a wide range of employers of all sizes including companies like Sonos, TripAdvisor, 23andMe, HelloFresh, Bowery Farms, Bristol Myers Squibb and non-profits from Sundance Film to The World Economic Forum. Learn more at www.mathison.io.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      USA

    • Year Invested

      2022

    • Team

  • MDDF is a medical device company focused on the manufacturing, development, and commercialization of high quality, affordably priced cardiovascular and general surgery medical devices for the Chinese market.

     

    • Category

      • MedTech
    • Status

      • Private
    • Location

      Beijing, China

    • Year Invested

      2011

    • Team

  • Medbanks (0314:HK) is building a data service platform for oncologists and cancer care centers in China. Learn more at www.medbanks.cn.

  • MediTrust Health is a provider of payment services for medical healthcare. The company is dedicated to helping patients solve their own medical payment problems through financial insurance, manage medical expenses more efficiently, and providing value to patients around medical finance, curative effect insurance, and drug benefits, helping patients manage their medical expenses. Learn more at www.meditrusthealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Shanghai, China

    • Year Invested

      2017

    • Team

  • Medwell Ventures Private Unlimited (“Medwell”) is an operator of specialty home healthcare services in India.

  • Menlo Therapeutics Inc. (NASDAQ: MNLO) is a late stage biopharmaceutical company focused on the development and commercialization of serlopitant for the treatment of pruritus (itch) associated with dermatologic conditions such as atopic dermatitis, psoriasis and prurigo nodularis.

  • Mersana Therapeutics (NASDAQ:MRSN) has its lead product candidate, XMT-1536, in clinical trials in patients with tumors expressing NaPi2b, including ovarian cancer, NSCLC, and other cancers. In addition, multiple partners are using Mersana’s platform to advance their ADC pipelines. Learn more at www.mersana.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2005

    • Team

  • Metcela is a clinical-stage Kanagawa-based biotech company bringing cell-based therapies to heart failure patients. Learn more at www.metcela.com.

  • Metsera is a clinical-stage biopharmaceutical company accelerating the next generation of medicines for obesity and metabolic diseases. Metsera is advancing a broad portfolio of oral and injectable incretin, non-incretin and combination therapies with potential best-in-class profiles to address multiple therapeutic targets and meet the future needs of a rapidly evolving weight loss treatment landscape. For more information, please visit us at www.metsera.com.

  • mindSHIFT is one of the largest IT outsourcing and cloud services providers.  The company has supported our clients with tailored and trusted technology solutions for more than 15 years. From day-to-day IT to major systems modernization, count on mindSHIFT’s technology expertise and personalized customer care for all of your IT needs. mindSHIFT was acquired by Roche Company in 2014.  Learn more at www.mindshift.com.

    • Category

      • Enterprise IT
    • Status

      • Acquired
  • Mineral Tree provides accounts payable automation software for finance professionals at growing organizations.  Mineral Tree was acquired by Global Payments in 2021.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      Cambridge, Massachusetts

    • Year Invested

      2012

    • Team

  • Modis Therapeutics, Inc. was formed in 2016 through a collaboration with academic experts in mitochondrial biology. The company’s lead program (MT1621) is in clinical development for thymidine kinase 2 deficiency (TK2d), an inherited mitochondrial disease. Modis Therapeutics is headquartered in Oakland CA, with offices in New York City. Modis was acquired by Zogenix.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Oakland, CA

    • Year Invested

      2018

    • Team

  • MoEngage is an intelligent customer engagement platform, built for the mobile-first world. With AI-powered automation, optimization capabilities, and in-built analytics, MoEngage enables hyper-personalization at scale across multiple channels like mobile push, email, in-app, web push, On-site messages, and SMS.  Fortune 500 brands across 35+ countries use MoEngage to orchestrate their cross-channel campaigns. Learn more at www.moengage.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA and Bengaluru, IND

    • Year Invested

      2020

    • Team

  • Mozper is bringing the weekly allowance into the digital era in Latin America. About 70% of the population in the region has never received formal financial education, and do not have the right tools to teach their children. In Brazil and Mexico alone, parents give more than $10B each year in pocket money to kids. Mozper offers a Visa debit card and an app where parents can give their kids an allowance, set spending rules (so they can’t blow it all on video games), assign chores and even create and track savings goals. Mozper is currently available in Mexico. Learn more at www.mozper.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Mexico City, MX

    • Year Invested

      2020

    • Team

  • Acknowledged by Forbes as one of the “Disruptive Technology Companies To Watch in 2019”, Mythical Games is enabling a gaming ecosystem that brings players, creators, brands and game developers together through personalized experiences and content. Led by gaming industry veterans, the team specializes in building games around player-owned economies and has helped develop major franchises including Call of Duty, World of Warcraft, Guitar Hero, Marvel Strike Force, Skylanders, and Minecraft: Story Mode. Learn more at mythicalgames.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2019

    • Team

  • Nanos Medical develops, manufactures and markets minimally invasive interventional therapy medical devices in the field of ENT, cardiovascular and others. Learn more at www.nanosmedical.com.

    • Category

      • MedTech
    • Status

      • Private
    • Location

      Shanghai, China

    • Year Invested

      2019

    • Team

  • In 1999, Napster changed the music industry forever when it launched the world’s first peer-to-peer music sharing service. Peaking at 85M users, for many, Napster was not only their first experience of digital music but also their first real social media experience. Napster is now once again gearing to revolutionize the music industry, evolving music streaming from being an access-based monthly subscription model to a social music platform and marketplace that connects artists and fans, unlocking unprecedented new creative and commercial opportunities. Learn more at www.napster.com.

  • Nebula Genomics is a human genome sequencing and health big data company on a mission to usher in the era of genomic sequencing by building a large and trusted genomic and health data marketplace for consumers, researchers and the medical community. Using blockchain to ensure that consumers maintain control of their data and are compensated for its use, the Nebula marketplace will aggregate a critical mass of rich genetic information that researchers can analyze in order to accelerate drug development, streamline clinical trials, and usher in the era of truly personalized medicine. Nebula Genomics was acquired by ProPhase Labs in 2021.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      San Francisco, CA and Boston, MA

    • Year Invested

      2018

    • Team

  • Neo4j is the leading graph database platform that drives innovation and competitive advantage at Airbus, Comcast, eBay, NASA, UBS, Walmart and more. Thousands of community deployments and more than 300 customers harness connected data with Neo4j to reveal how people, processes, locations and systems are interrelated. Using this relationships-first approach, applications built using Neo4j tackle connected data challenges including artificial intelligence, fraud detection, real-time recommendations and master data. Find out more at neo4j.com.


    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Mateo, CA and Malmö, Sweden

    • Team

  • Neumora Therapeutics, Inc. (NASDAQ: NMRA) is a clinical-stage biotechnology company pioneering precision medicines for brain diseases through the integration of data science and neuroscience. Neumora is redefining neuroscience research and development with a data-driven precision neuroscience platform to cut through brain disease heterogeneity to match the right patient populations to targeted therapeutics. The Company’s precision data science platform integrates multiple data types to define patient subtypes through the development of Data Biopsy Signatures™ and Precision Phenotypes™.  Learn more at www.neumoratx.com.

  • NeuroSmart is an operator of an education and research center focusing on autism. The company helps patients with autism through scientific research and early intervention application, providing families with a comprehensive scientific family intervention program.

    Learn more at neurosmartinc.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Zhejiang, China

    • Year Invested

      2021

    • Team

  • NextWave Pharmaceuticals is a specialty pharmaceutical company seeking to create and promote differentiated products in the pediatric market. NextWave Pharmaceuticals was acquired by Pfizer.

  • NFlection Therapeutics is a biopharmaceutical company focused on the development of therapies for Neurofibromatosis 1 (NF1), and other disorders. Learn more at https://nflection.com/.

  • NOCD is the #1 telehealth provider for the treatment of obsessive-compulsive disorder (OCD) and the leading Community-Driven Therapy company. The company helps people reclaim their lives with clinically proven OCD treatment by removing barriers to care, and by reducing the stigma associated with OCD. Inside the NOCD platform, members can quickly access a national network of licensed therapists that specialize in Exposure and Response Prevention (ERP), the “gold standard” for OCD treatment. Learn more at www.treatmyocd.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Chicago, IL

    • Year Invested

      2021

    • Team

  • Nocion Therapeutics, a neuroinflammation and analgesic company discovering and developing novel pharmaceutical treatments for various indications including pain, cough and itch.  Learn more at www.nociontx.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Cambridge, MA

    • Year Invested

      2019

    • Team

  • NodThera is a biotech engaged in innate immune/inflammasome research. Our leading project is focused on developing inhibitors of the NLRP3 inflammasome for the treatment of inflammatory and neuroinflammatory diseases. Learn more at www.nodthera.com

  • Notabene is a reg-tech compliance SaaS solution that connects the traditional financial industry and crypto industry. The company works to make crypto transactions a part of the everyday economy by providing software, tools, and comprehensive data to manage regulatory and counterparty risks in crypto transactions. To learn more, visit www.notabene.id.

  • Notable is an AI powered healthcare company that puts appointments on autopilot. By analyzing historical patterns of practice, Notable proactively automates away hundreds of manual repetitive tasks like adding diagnoses, orders, templates, billing codes, and more. Learn more at www.notablehealth.com.

  • NovaMed Pharmaceuticals is a revenue-generating specialty pharmaceutical company focused on the commercialization of branded innovative therapies for diseases with high unmet medical need in China, including oncology, urology, and cardiovascular.  NovaMed was acquired by SciClone.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Shanghai, China

    • Year Invested

      2007

  • Nuance Communications is a multinational computer software technology corporation that provides speech and imaging applications. Nuance Communications went public (NASDAQ:NUAN) in 1995Learn more at www.nuance.com.

    • Category

      • Enterprise IT
    • Status

      • Public
    • Location

      Burlington, MA

  • Nvelop Therapeutics was founded in 2022 to address the challenge of efficiently delivering therapeutic cargoes to target cells in vivo. Nvelop’s next-generation platforms enable highly efficient and cell-specific in vivo delivery of a wide range of cargoes to many types of target cells. The two platforms were independently developed in the labs of scientific co-founders and gene editing pioneers Dr. David Liu of the Broad Institute of MIT and Harvard, and Dr. Keith Joung at Massachusetts General Hospital. With its own pipeline of therapeutics and through strategic collaborations, Nvelop aims to use these programmable, non-viral platforms to transform delivery for a broad range of genetic medicines and modalities in order to treat many previously undruggable diseases. For more information, visit www.nveloptx.com.

  • Oakley Networks was a leader in insider threat protection, combining network and endpoint monitoring with targeted investigations to protect enterprises. Oakley Networks was acquired by Raytheon in 2007.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Salt Lake City, UT

  • Odaseva partners with the largest and most sophisticated organizations in the world to accelerate their trust in business-critical cloud applications. Fortune Global 500 industry leaders use Odaseva technology to back up and restore data, ensure data privacy and regulatory compliance, and use data to drive operational agility. Engineered for Salesforce by Salesforce experts and endorsed by Salesforce Ventures, Odaseva is trusted by 30+ million users and has received 100% five-star reviews over eight years on the Salesforce AppExchange.  Learn more at www.odaseva.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Paris, France and San Francisco, CA

    • Year Invested

      2020

    • Team

  • OnCusp Therapeutics, Inc., headquartered in New York City, is a biopharmaceutical company dedicated to transforming cutting-edge preclinical innovation into clinically validated treatments for cancer patients worldwide. OnCusp was co-founded by Dr. Bing Yuan, Dr. Eric Slosberg, and Dr. Andy Fu, and has built a strong team of accomplished veterans with proven track records in building startup biotechs, leading successful preclinical and clinical programs, and creating value through global partnerships. The company is committed to accelerating the advancement of globally competitive oncology assets for patients. Learn more: https://www.oncusptx.com/

  • Founded in 2018, OpenNode is the world’s leading bitcoin payment processor and infrastructure provider, connecting the world with revolutionary payment technology. OpenNode provides secure, reliable bitcoin payment acceptance and payout solutions for businesses, platforms, and people everywhere. From payment buttons to hosted checkout, and e-commerce plug-ins to optimized APIs, OpenNode offers the benefits of instant, lowest cost payments made possible by Bitcoin, the world’s best decentralized payment network; and the Lightning Network, Bitcoin’s leading scaling solution. Learn more at www.opennode.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2020

    • Team

  • The unique makeup of the Optimus Ride team includes over 30 years of shared experience on the cutting edge of interdisciplinary research in self-driving technologies, electric vehicles, mobility-on-demand and other transportation systems. The team also has a decade of industrial and entrepreneurial experience spanning manufacturing robots, medical robots, shared vehicle fleet management and urban design. Building on this significant knowledge, the company will continue to leverage the latest advances in complex sensor fusion, mapping, computer vision and machine learning to ultimately deploy a new form of transportation system that enables safe, sustainable and equitable mobility access. This company was acquired by Magna in 2022.

  • Orchard Therapeutics (NASDAQ: ORTX) is a fully integrated commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies. Learn more at www.orchard-tx.com.

  • OriGynMED is a developer of medical devices designed for women’s health. The company is mainly engaged in developing various gynecology medical devices such as hysterectomy cold knife and functional hysteroscope, enabling client to improve treatment effect. Learn more at www.origynmed.com.

    • Category

      • MedTech
    • Status

      • Private
    • Location

      Hangzhou, China

    • Year Invested

      2015

    • Team

  • Orient Speech Therapy Limited (“OST”) is a Hong-Kong based healthcare services provider that operates a chain of private speech therapy clinics in China. Learn more at www.dfqy.com.

  • Oviva is a new type of healthcare provider using technology to scale the dietitian workforce to help meet the growing number of patients with diet-related health conditions. Learn more at www.oviva.com/uk/.

  • Owkin combines life-science and machine learning expertise to make drug development and clinical trial design more targeted and more cost effective. Owkin’s machine learning algorithms create models that predict disease evolution and treatment outcomes. These predictive models are implemented in clinical trials for enhanced analysis, surrogate endpoints, patient stratification, patient selection, and high-value subgroup identification. The impact of this research is faster discovery of better treatments at a lower cost. Learn more at www.owkin.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2019

    • Team

  • OwnCloud is the leading enterprise grade, open source file-sync and share platform. The company focuses on giving end-users the flexibility to access files anywhere while giving IT departments greater control of their data. Learn more at www.owncloud.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Nüremberg, Germany, and Lexington, MA

    • Year Invested

      2013

  • OZiva is a plant-based Clean Nutrition Brand. The brand’s core differentiator lies in building a nutrition & fitness ecosystem that combines the best of ancient sciences such as Ayurveda, modern micronutrients, and an instantaneous digital community altogether.  Learn more at www.oziva.in.

  • Papaya Payments is a free and easy way to pay your bills. Just snap a photo of a paper bill and Papaya will automatically validate it and facilitate your payment. Learn more at www.papayapayments.com.

    • Category

      • FinTech
      • Health IT/Services
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2018

    • Team

  • Paradigm is a unified, non-custodial liquidity network for crypto derivatives traders across CeFi and Defi. The free-to-use platform provides a single point of access to multi-asset, multi-leg, multi-protocol liquidity on-demand, without compromising on price, size, execution costs and immediacy. Learn more at paradigm.co.

  • Paradigm is rebuilding the clinical research ecosystem by creating a platform that enables equitable access to trials for all patients, while enhancing trial efficiency and reducing the barriers to participation for healthcare providers. Paradigm aims to break down barriers across the trial ecosystem through one seamless infrastructure implemented at healthcare provider organizations, bringing potentially life-saving therapies to patients faster. Learn more: www.paradigm.inc.

  • Parrot is a Mexican food tech startup that helps the country’s restaurants to digitize and optimize their operations through technology. Its ParrotConnect solution is an all-in-one platform for today’s restaurants: multi-brand and multi-channel, which allows the user to manage all business tasks from one device. Integrate orders from delivery apps, table service and take-away orders on the same screen, configuration of personnel permissions, menu editor, kitchen areas, types of payment, cashier operations, and real-time reports from a single management portal. Learn more at pos.parrotsoftware.io.

  • Path provides retail investors the ability to invest in broad based baskets of crypto assets, access to trading bots, and automated portfolio management tools. The company offers direct access to curated, pre-built portfolios that are easily integrated to a customer’s exchange account with automatic purchasing and rebalancing. Learn more at www.pathcrypto.com.

  • PatientPing is a care coordination platform that reduces the cost of healthcare by seamlessly connecting providers to coordinate patient care. Patient Ping was acquired by Appriss Health in 2021.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Boston, MA

    • Year Invested

      2015

    • Team

  • Patina is reinventing primary care for older adults and those who care for them, so everyone gets the healthcare and aging experience they deserve. Learn more at www.patinahealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Bala Cynwyd, PA

    • Year Invested

      2021

    • Team

  • Pediatrix Therapeutics is a pharmaceutical company focused on the field of pediatrics by developing and introducing effective and clinically proven children’s medicines to provide Chinese children and families with high-quality and affordable treatment options.

    Learn more at pediatrixtherapeutics.com.

  • Peptone is an innovative drug discovery company applying advanced biophysics, atomic-level experimental approaches, cutting-edge supercomputing and machine learning to the challenge of biopharmaceutical research and development. By bringing these proprietary approaches together, we are exploring the world of intrinsically disordered proteins (IDPs) – proteins without a fixed structure that play a significant role in health and disease – opening up the possibility of novel therapeutics against an entire class of high value and previously undruggable targets. Learn more at peptone.io.

  • Percy works at the intersection of design, development, and deployment. Their product is the world’s first truly continuous visual testing platform, helping enable product teams to ship software faster and with confidence in every visual change to their application. Learn more at percy.io.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2019

    • Team

  • PharmEasy is one of India’s largest healthcare delivery platforms. The company helps patients connect with local pharmacy stores and diagnostic centers in order to fulfill their medical needs. Learn more at www.pharmeasy.in.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Mumbai, India

    • Year Invested

      2018

    • Team

  • Ping Identity provides cloud-based identity management software for companies and government organizations. Ping Identity was acquired by Vista Equity Partners in 2016. Learn more at www.pingidentity.com.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Denver, CO

  • Plasmagen is an Indian biopharma company that specializing exclusively in Plasma Protein Therapy. Learn more at www.plasmagen.in.

  • Founded in late 2016 by former Baidu Chief Architect James Peng (CEO) and programming legend Tiancheng Lou (CTO), Pony.ai aims to revolutionize the future of transportation by building the safest and most reliable self-driving technology.  To learn more, visit pony.ai.

    • Category

      • FrontierTech
    • Status

      • Private
  • Precision Biosciences (NASDAQ:DTIL) is developing a gene-editing platform based on their proprietary ARCUS nuclease for multiple applications with a focus on human therapeutics. Learn more at www.precisionbiosciences.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Durham, NC

    • Year Invested

      2015

  • Prime Medicine (NASDAQ: PRME) is a biotechnology company founded to deliver on the promise of Prime Editing, a versatile gene editing technology that can truly “search and replace” to restore normal genetic function and address the fundamental causes of disease. Prime Medicine envisions a world where Prime Editing can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients and shaping the future of gene editing. Learn more at www.primemedicine.com.

     

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2019

    • Team

  • Promentis Pharmaceuticals, Inc., a privately-held biopharmaceutical company, is developing innovative therapies for neuropsychiatric disorders. Learn more at www.promentispharma.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Milwaukee, Wisconsin

    • Year Invested

      2016

    • Team

  • Prosper’s mission is to advance financial well-being. The company’s online lending platform connects people who want to borrow money with individuals and institutions that want to invest in consumer credit. Borrowers get access to affordable fixed-rate, fixed-term personal loans. Investors have the opportunity to earn solid returns via a data-driven underwriting model. To date, over $13 billion in personal loans have been originated through the Prosper platform for debt consolidation and large purchases such as home improvement projects, medical expenses and special occasions. Learn more at www.prosper.com

    • Category

      • FinTech
    • Status

      • Private
    • Location

      San Francisco, CA

  • The Protenus healthcare compliance analytics platform uses artificial intelligence to help partner hospitals make decisions about how to better protect their data, their patients, and their institutions. Learn more at www.protenus.com.

  • Proteostasis Therapeutics (NASDAQ: PTI)  is a drug discovery company developing small molecule therapeutics to treat cystic fibrosis and other diseases caused by dysfunctional protein processing.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Cambridge, MA

    • Year Invested

      2008

    • Team

  • Proximie is a technology platform that uses a combination of machine learning, artificial intelligence and augmented reality to allow clinicians to virtually ‘scrub in’ and collaborate with each other from anywhere in the world.  Learn more at proximie.com.

  • Puffer is defining a new industry standard for secure validator operations with the primary objective of preserving decentralization, with Anti-Slashing technologies designed to minimize the chance of slashing events. The company’s Secure-Aggregator technology provides the foundation to build a secure, scalable, and performant liquid staking protocol. Allowing permissionless and capital-efficient Node Operator (NoOp) participation allows anyone to join the PufferPool to help preserve Ethereum’s decentralization. Learn more at www.puffer.fi.

  • Pulmocide is a biopharmaceutical company with a mission to treat common acute and chronic respiratory tract infections associated with serious complications and devastating effects on patients’ quality of life. Learn more at www.pulmocide.com.

  • Quantum Circuits, Inc. (QCI) was founded in 2015 with the goal of developing, manufacturing and selling the first practical and useful quantum computers based on superconducting devices. QCI was founded by pioneers in quantum devices and information processing from the Department of Applied Physics at Yale University. Their group has produced many scientific firsts, including the development of a “quantum bus” for entangling qubits with wires and the first implementation of a quantum algorithms and error-correction with a solid-state device. Learn more: www.quantumcircuits.com

  • Quartet Health is developing care coordination software and services designed to improve clinical outcomes and reduce the cost of care for patients where behavioral health is the primary or a comorbid condition. Learn more at www.quartethealth.com

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2015

    • Team

  • Quovo is a data platform providing connectivity to consumer financial accounts. Quovo centralizes, organizes, and enriches data from millions of accounts across more than 14,000 institutions to provide businesses with a comprehensive picture of each customers’ financial identity. With industry-specific solutions, clients from emerging fintech startups to Fortune 500 companies rely on Quovo for its seamless technology and rich data insights to deliver more personalized and frictionless customer experiences. Quovo’s unparalleled coverage of the financial ecosystem, powerful data analytics, and flexible deployment options propel businesses in uncovering opportunities to grow their relationships with customers. Quovo was acquired by Plaid in 2019. Learn more at www.quovo.com.

  • Rallybio (NASDAQ: RLYB) is a biopharmaceutical company focused on identifying and accelerating the development of life-transforming therapies for patients with severe and rare disorders. Learn more at www.rallybio.com.

  • RareCyte offers Precision Biology solutions focused on multiplexed analysis of cells and tissue with applications in both research and clinical diagnostics. The Company has deep experience in developing advanced precision life science systems used in cutting-edge labs worldwide. RareCyte customers perform innovative research, bring new therapeutics to market, and perform a wide range of single cell applications in oncology and disease research. Learn more at www.rarecyte.com.

  • RareStone (formerly Citrine Medicine) is a rare disease-focused therapeutics company focused on the Greater China market that was co-founded by Eight Roads Ventures, F-Prime Capital and Vivo Capital. RareStone is dedicated to improving the lives of rare disease patients by making diagnosis and essential treatments available and accessible for those who need them. Learn more at www.rarestonegroup.com.

  • ReadMe provides an easy-to-configure platform for companies to document and showcase their Application Programming Interface (API), and build loyal, productive developer communities. Learn more at www.readme.io.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2015

    • Team

  • RDC (Receipts Depositary Corporation) is the first depositary that aims to make it as easy for QIBs to own digital and alternative assets as traditional securities. Using the DR construct that has been trusted by investors for nearly a century, the RDC platform provides asset protection, transparency, risk minimization and operational ease. RDC is not a bank and is not registered as a broker, dealer or investment adviser in any jurisdiction. Learn more at receiptsdepo.io.

  • Recurly, Inc. delivered enterprise-grade subscription management to thousands of SaaS, media, mobile, consumer goods, productivity, and publishing businesses worldwide. Businesses like Sling TV, Asana, Unbounce, and BarkBox were dependent on Recurly’s ability to cut through the complexity of subscription management to drive recurring revenue growth. Since its launch in 2010, Recurly had deployed subscription billing for thousands of companies across 32 countries, making it the most trusted subscription management platform. Recurly was acquired by Accel-KKR in 2020.

    • Category

      • Enterprise IT
      • FinTech
    • Status

      • Acquired
    • Location

      San Francisco, CA

    • Year Invested

      2014

    • Team

  • REDPINE is a medical technology company that provides complete solutions for medical business. It focuses on the research and development and production of single-use Class III medical devices, initially endoscopes for urology and gynecology. Learn more at en.gzredpine.com.

  • ReGenX Biosciences (NASDAQ: RGNX)  is a leading AAV (adeno-associated virus) gene therapy company with a broad platform technology based on its proprietary NAV vector technology platform Learn more at www.regenxbio.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Washington, D.C.

    • Year Invested

      2013

  • RespiVert was a drug discovery and development company focused on inhaled therapies for severe respiratory disease. RespiVert was acquired by Centocor Ortho Biotech – a division of Johnson & Johnson.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      London, UK

    • Year Invested

      2007

    • Team

  • Rialtic is an enterprise software platform empowering health insurers and healthcare providers to run their most critical business functions. Rialtic’s best-in-class payment accuracy product brings programs in-house and helps health insurance companies gain total control over processes that have been managed by disparate and misaligned vendors. Currently working with leading healthcare insurers and providers, the company is tackling a $1 trillion problem to reduce costs, increase efficiency and improve quality of care. Learn more at www.rialtic.io.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Atlanta, GA

    • Year Invested

      2020

    • Team

  • RightHand Robotics (RHR) builds a data-driven intelligent picking platform, providing flexible and scalable automation for predictable order fulfillment. The software-driven, hardware-enabled modular solution is capable of adapting to any picking situation bringing reliability to order fulfillment in growing industries such as electronics, apparel, grocery, pharmaceuticals, and more. Learn more at www.righthandrobotics.com.

    • Category

      • Enterprise IT
      • FrontierTech
    • Status

      • Private
    • Location

      Somerville, MA

    • Year Invested

      2020

    • Team

  • RIGImmune is a platform biopharmaceutical company developing a novel investigational class of RNA immunotherapies termed “SLRs” for the potential pan-viral treatment and prophylaxis of viral respiratory diseases and selected cancers. The RIGImmune development candidates act to specifically modulate RIG-I, a host surveillance pathway that triggers the innate immune system to enhance an intrinsic response to RNA viruses, including influenza, RSV, rhinovirus, and SARS-CoV-2, and tumor DNA. The lead development candidate at RIGImmune is RIG-101.

    The company was co-founded by the prominent Yale University professors, Anna Marie Pyle, Ph.D. and Akiko Iwasaki, Ph.D., who currently serve as scientific advisors to the company. Dr. Pyle co-discovered the RIG-I receptor family and conducted many of the first structural and biochemical investigations on the cytosolic protein, RIG-I. Dr. Pyle is also a specialist in RNA structure and design. She designed the stem-loop RNA therapeutics (SLR) for selective targeting of RIG-I using crystal structure data of RIG-I complexed with RNA and developed them as antitumor and anticancer compounds in collaboration with Dr. Iwasaki, whose expertise in mucosal immunity has been highly sought during the COVID-19 pandemic.

    RIGImmune is a UConn Technology Incubation Program (TIP) company located in Farmington, CT, was founded by Yale scientists, and has an experienced management team of successful biotech entrepreneurs and world-renowned scientists. Learn more at rigimmune.com.

  • Rippl is a new kind of mental health company focused on seniors and obsessed with its clinicians. Seniors with mental health challenges, especially neurocognitive conditions like Alzheimer’s disease and other dementias, are overlooked and under cared for, often without access to high quality, real-time, practical care. Leveraging a value-based approach, disruptive technology, and a relentless focus on empowering and enabling its clinicians, Rippl is pioneering a new care model to dramatically expand access to high quality, wraparound mental health care for seniors, their families, and caregivers. Rippl provides 24/7 support and personalized care when and where they need it – on the phone, online or in their living rooms. Learn more at www.ripplcare.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Seattle, WA

    • Year Invested

      2022

    • Team

  • RiskLens is the leading provider of quantitative cyber risk management software. Its platform is recognized as a mission-critical business application for cybersecurity and risk teams across the Fortune 1,000. RiskLens empowers large enterprises and government organizations to manage cyber risk from the business perspective by quantifying that risk in monetary terms. Clients depend on RiskLens solutions to better understand and communicate their cyber risk exposure in financial terms, prioritize their risk mitigations, measure the ROI of their security investments, and meet regulatory demands calling for the quantification of cyber risk. RiskLens is the only cyber risk quantification software purpose-built on FAIR, the standard quantification model for information security and operational risk. Learn more at www.risklens.com.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Reston, VA

    • Year Invested

      2019

    • Team

  • RiskRecon is the only continuous vendor monitoring solution that delivers risk-prioritized action plans custom-tuned to match your risk priorities, providing the world’s easiest path to understanding and acting on third-party cyber risk. Partner with RiskRecon to build your scalable, third-party risk management program to realize dramatically better risk outcomes. RiskRecon was acquired by Mastercard in 2019.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Salt Lake City, UT

    • Year Invested

      2017

    • Team

  • Sana Biotechnology, Inc. (NASDAQ:SANA) is focused on creating and delivering engineered cells as medicine for patients. We are a team of scientists, clinicians and biotechnology veterans focused on creating an enduring company that makes meaningful medicines and changes how we approach treating disease. Learn more about Sana at www.sana.com.

  • Securonix is working to radically transform all areas of data security with actionable security intelligence. Their purpose-built, advanced security analytics technology mines, enriches, analyzes, scores and visualizes customer data into actionable intelligence on the highest risk threats from within and outside their environment. Using signature-less anomaly detection techniques that track users, account and system behavior, Securonix is able to detect the most advanced insider threats, data security and fraud attacks automatically and accurately. Learn more at www.securonix.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Dallas, TX

    • Year Invested

      2017

    • Team

  • Seis is banking for the 44 million native Spanish speakers living in the US. Their mission is to build the most delightful, full-service banking experience for anyone who wants to bank in their native Spanish. Their goal is to make such an amazing banking experience that people will wish they spoke Spanish so they could bank with Seis. They’ll treat Spanish speakers as first-class citizens & end “dial 2 for Español”. Learn more at seis.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Salt Lake City, UT

    • Year Invested

      2022

    • Team

  • Semma Therapeutics is a regenerative medicine company founded to develop transformative stem cell-derived therapies to provide a functional cure for patients with diabetes. This company was acquired by Vertex in 2019.

  • Seyond (formerly Innovusion) is a leading developer of image-grade LiDAR sensor systems for level 4+ of the autonomous vehicle market. Its unique combination of range, resolution, hardware accelerated sensor fusion, compact size, ease of integration and cost effectiveness makes its products an ideal choice for the most demanding applications. Learn more at seyond.com.

    • Category

      • FrontierTech
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2018

    • Team

  • Shift Bioscience (Shift) is a Cambridge, UK-based biotechnology company focused on safe cellular reprogramming for rejuvenation. The company leverages a proprietary cellular age clock and an active machine learning approach to discover novel factors for safer cellular rejuvenation without the use of pluripotency-inducing reprogramming genes. Shift aims to enable the development of reprogramming-based therapeutics to prevent and treat age-associated diseases. Learn more at www.shiftbioscience.com.

  • Shinobi Therapeutics is a biotechnology company developing a new class of off-the-shelf immune evasive iPSC-derived cell therapies. Based on the research of scientific co-founders Shin Kaneko, M.D., Ph.D., at Kyoto University and Tobias Deuse, M.D., at University of California, San Francisco, Shinobi has created a new allogeneic CD8αβ iPS-T cell platform that demonstrates comprehensive immune evasion from all arms of the immune system. For more information, please visit www.shinobitx.com.

  • Silexon is an emerging AI-empowered technology company which aims to create an open AI platform for strategic collaboration in order to facilitate data-driven life science research and empower drug R&D process, and ultimately provide patients with greater access to innovative drugs for unmet medical needs.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Nanjing, China

    • Year Invested

      2021

    • Team

  • Silq is on a mission to bring radical visibility and real-time data from the factory floor to brands around the world. We power sourcing, manufacturing and shipping for apparel, footwear, home goods and accessory brands. Our on-site experts provide real-time updates into the production process directly from the factory floor. Paired with Silq’s proprietary technology platform, brands are able to accelerate speed-to-market and improve product quality. Our customers include direct-to-consumer (DTC) and wholesale fashion and apparel brands such as Barry’s, Mightly, Mizzen+Main and Lambert in addition to design and production houses such as Pinpoint Merchandising and Stars Design Group. Learn more at www.onesilq.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2022

    • Team

  • Simon Data is the first and only enterprise customer data platform with a fully-integrated marketing cloud. Moving beyond the limitations of both categories, Simon’s platform empowers businesses to leverage enterprise-scale big data and machine learning to power customer communications in any channel. Simon’s unique approach allows brands to develop incredible personalization capabilities without needing to build and maintain massive bespoke data infrastructure. Learn more at www.simondata.com.

  • Singular Genomics (NASDAQ: OMIC) is developing a new next generation sequencing platform. Learn more at www.singulargenomics.com.

  • Sironax is a developer of pharmaceuticals for inflammatory and neuro-degenerative diseases. The company researches apoptosis and other cell death pathways to develop quality pharmaceuticals, enabling healthcare professionals to prescribe advanced treatments to their patients.

    Learn more at sironax.com.

  • 66nao provides a cloud based platform for digital brain assessment and training. Learn more at www.66nao.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Beijing, China

    • Year Invested

      2016

  • Skyline Therapeutics (formerly Geneception) is a fully-integrated gene and cell therapy based in Hangzhou and Shanghai, China.  Founded by F-Prime Capital, Eight Roads Ventures China and Lilly Asia Ventures in 2018, Skyline’s mission is to become a preeminent gene and cell therapy company, working to deliver world-class therapeutics for patients in China and globally.

    Learn more at skytx.com.

  • Founded in 2013, Snapdocs is the industry’s leading digital closing platform. With its patented AI technology, Snapdocs is on a mission to perfect mortgage closings and transform a $2 trillion pillar of the U.S. economy. Powering over 750,000 closings a year, Snapdocs is leading the charge to modernize, streamline, and improve the mortgage process for lenders, borrowers, and settlement. Snapdocs is the only solution with a proven track record of creating a single, scalable process for every closing, whether wet, hybrid, or digital. Every day, over 50,000 mortgage professionals rely on Snapdocs’ technology to automate manual work and digitize paper processes that plague the industry. Snapdocs is a rapidly growing San Francisco based real estate technology company backed by prestigious Silicon Valley blue-chip venture capital funds, like Y Combinator, SV Angel, Sequoia Capital, and F-Prime Capital. Learn more at www.snapdocs.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2019

    • Team

  • Snapsheet is the leading provider of virtual claims solutions, using powerful technology to improve workflows for more than 60 insurance carriers around the world. Snapsheet creates a simple claims process, starting with virtual estimations all the way to final repairs and payment, by streamlining communication between consumers, shops and carriers. Snapsheet takes complicated processes and makes them fast and simple for everyone involved. Learn more at www.snapsheetapp.com.

  • Solidus Labs is the category-definer for crypto-native triple T (T3) market integrity solutions – trade surveillance, transaction monitoring, and threat intelligence. Their mission is to enable safer crypto trading throughout the investment journey across all centralized and DeFi markets. As the founder of industry leading initiatives like the Crypto Market Integrity Coalition and DACOM Summit, and in everything they do, Solidus is deeply committed to ushering in the financial markets of tomorrow. Learn more at www.soliduslabs.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2021

    • Team

  • Solv Protocol is a leading Bitcoin staking platform, powered by its innovative Staking Abstraction Layer. Solv allows Bitcoin holders to gain access to a diverse set of yield opportunities without sacrificing liquidity and enables seamless participation within DeFi ecosystems. Learn more at Solv.Finance.

  • SonderMind enables consumers to quickly find and access a trusted, well-matched therapist, while enabling therapists to focus on providing excellent patient care, not worrying about administrative and billing issues.  Learn more at www.sondermind.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Denver, CO

    • Year Invested

      2020

    • Team

  • Space and Time is the first decentralized data warehouse that delivers sub-second ZK proofs against onchain and offchain data to power the future of AI x blockchain. Learn more at spaceandtime.io.

  • SpectrumAi is a digital health company innovating Autism care to increase access to high-quality ABA therapy for kids on the spectrum around the world. With support from industry veterans in technology and healthcare, SpectrumAi is working with global clinical leaders in ABA therapy, parents, and payers to modernize. Learn more at www.spectrumai.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Los Angeles, CA

    • Year Invested

      2022

    • Team

  • Spry is a purpose built platform for the physical rehabilitation industry. It helps therapists streamline care delivery, increase patient inflow and reduce administrative costs while also helping patients improve outcomes by making it easy to understand and follow care plans. Spry has been able to achieve this by using physical rehabilitation specific workflows, advanced computer vision technology and new age product design paradigms. Learn more: www.sprypt.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Mumbai, India

    • Year Invested

      2022

    • Team

  • Stage is on a mission to empower builders and innovators to create enduring technology. Stage is a dynamic monetization platform for early- and growth-stage software companies. Starting with flexible plans and paywalls, the platform gives product teams the ability to understand, measure, and capture value from customers with confidence. Stage was co-founded by CEO Patrick Despres-Gallagher and CTO Kaiser Leib in October 2021 with remote operations and hubs in California and Montana. Patrick was previously one of the early Product Managers at Loom and RapidSOS as well as a family office investor focused on enterprise software. Kaiser was previously an early Software Engineer at Juniper Square and SoFi. Learn more at www.heystage.com and follow them on Twitter and LinkedIn.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2022

    • Team

  • Stride Health is an early-stage healthcare IT company developing a multi-carrier, private health insurance marketplace for the individual segment. Learn more at www.stridehealth.com.

    • Category

      • FinTech
      • Health IT/Services
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2014

    • Team

  • Structure Therapeutics (NASDAQ: GPCR) is a clinical-stage global biopharmaceutical company discovering and developing novel oral therapeutics to treat a wide range of chronic diseases with unmet medical needs.  Learn more at www.structuretx.com.

  • Surface Oncology (NASDAQ:SURF) is an immuno-oncology company developing next-generation antibody therapies focused on the tumor microenvironment with lead programs targeting CD73, CD39, IL-27 and CD47. Surface Oncology was acquired by Coherus BioSciences.

  • Symbiomix developed the first oral, single dose treatment in the United States for bacterial vaginosis (BV), a common gynecological infection that increases the risk of serious health problems. Symbiomix was acquired by Lupin Pharmaceuticals. Learn more at www.symbiomix.com.

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Newark, NJ

    • Year Invested

      2013

    • Team

  • T-Therapeutics is a next-generation T cell receptor (TCR) company spun off from the University of Cambridge. The company was created to harness the power of T cell biology, evolved over millions of years, to create safe and effective treatments for many cancers and autoimmune diseases. Learn more: https://t-therapeutics.com/

  • TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven and physics-based high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution. Learn more at www.tandemai.com.

    • Category

      • Therapeutics
    • Status

      • Private
    • Location

      Shanghai, China and New York, NY

    • Year Invested

      2023

    • Team

  • TCT Medical is a diagnostic company based in China which provides high quality diagnostic tests, primarily in the women’s health arena. TCT Medical was acquired by Hologic.

    • Category

      • MedTech
    • Status

      • Acquired
    • Location

      Beijing, China

    • Year Invested

      2009

    • Team

  • Teleo is revolutionizing heavy equipment operations by turning construction and mining equipment into semi-autonomous robots. Their Teleo Supervised Autonomy technology lets contractors operate existing heavy equipment without an operator in the cab, letting a single operator control multiple pieces of equipment from a remote desk. This increases productivity, safety, and operator satisfaction — critical challenges in the construction and mining industries. Teleo is backed by UP.Partners, F-Prime Capital, K9 Ventures, YCombinator and a host of industry luminaries. Learn more at teleo.ai.

  • Tempest Therapeutics (Nasdaq: TPST) is a development-stage biotechnology company advancing small molecule therapeutics that modulate anti-tumor immunity pathways. Learn more at www.tempesttx.com.

  • Tenpoint Therapeutics is a biotechnology company committed to advancing engineered cell-based therapies and in vivo reprogramming to restore vision for people with degenerative ocular diseases, bringing together the global experts who are shaping the regenerative ocular medicine revolution and the technologies that are driving it. The company is addressing the ultimate cause of vision loss by replacing diseased cells with healthy ones to permanently restore vision. Learn more: www.tenpointtx.com.

  • Tetraphase (NASDAQ: TTPH)  is a biopharmaceutical company using its proprietary chemistry technology to create novel antibiotics for serious and life-threatening bacterial infections; its lead product XERAVATM (eravacycline) is approved for the treatment of complicated intra-abdominal infections by the FDA and EMA. Tetraphase Pharmaceuticals was acquired by La Jolla Pharmaceutical Company.

  • The Giving Block, a Shift4 company, is the platform helping nonprofits fundraise more effectively from modern philanthropists. Pioneers of the “Crypto Philanthropy” movement, The Giving Block developed the leading solutions for cryptocurrency donations, taking crypto and NFT donations mainstream in the nonprofit sector. The Giving Block’s team then developed a stock giving experience built to empower even more donors to give non-cash assets. When combined, The Giving Block’s product suite empowers more donors than ever to give assets to their favorite causes. Today, thousands of nonprofits are using The Giving Block to fundraise from modern philanthropists. Learn more at www.thegivingblock.com.

    • Category

      • Crypto
    • Status

      • Acquired
    • Location

      Miami, FL

    • Year Invested

      2021

    • Team

  • Threat Stack enables growth-driven companies to scale securely and meet complex cloud security needs by identifying and verifying insider threats, external attacks, and data loss in real time. With a comprehensive approach to intrusion detection, Threat Stack empowers security and operations to better manage risk and compliance across their entire infrastructure, including cloud, hybrid cloud, multi-cloud, and containerized environments. Threat Stack was acquired by F5 Networks in 2021.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Boston, MA

    • Year Invested

      2017

    • Team

  • Launched in 2013, Toast powers successful restaurants of all sizes with a technology platform that combines restaurant POS, front of house, back of house and guest-facing technology with a diverse marketplace of third-party applications. By pairing technology with an unrivaled commitment to customer success, Toast helps restaurants streamline operations, increase revenue and deliver amazing guest experiences. Toast was named to the 2018 Forbes Cloud 100 and recognized as the third fastest-growing technology company in North America on the 2017 Deloitte Fast 500. Toast went public in 2021 (NYSE:TOST). Learn more at www.toasttab.com.

    • Category

      • Enterprise IT
      • FinTech
    • Status

      • Public
    • Location

      Boston, MA

    • Year Invested

      2016

    • Team

  • Tokensoft was founded in 2017 on three pillars: compliance, scalability and cybersecurity. They’re proud to continue to uphold these values today as we bring the future of web3 to mainnet. To date, Tokensoft has partnered with projects such as Avalanche, Arbitrum and the Graph to help build their communities, the right way. Learn more at www.tokensoft.io.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      Austin, TX

    • Year Invested

      2018

    • Team

  • Toku is a Chile-based payment orchestration company that offers a solution for collecting recurring payments in LatAm. It has three main value propositions: 1) increase payment acceptance rate via dynamic routing; 2) incur the lowest possible cost by using account-to-account payment; 3) have the best-automated payment experience. Learn more at trytoku.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Santiago, Chile

    • Year Invested

      2021

    • Team

  • Topaz Pharmaceuticals is a specialty pharmaceutical company developing a topical prescription product, Sklice, for the treatment of head lice. Topaz Pharmaceuticals was acquired by Sanofi.

     

  • TraceLink the world’s largest Track and Trace Network for connecting the life sciences supply chain and providing real-time information sharing for better patient outcomes. Learn more at www.tracelink.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Wakefield, MA

    • Year Invested

      2015

    • Team

  • TradeBlock serves financial institutions with execution and analysis tools that capitalize on the incredible potential of block chain technologies. TradeBlock was acquired by CoinDesk in 2021.

    • Category

      • Crypto
    • Status

      • Acquired
    • Location

      New York, NY

    • Year Invested

      2014

    • Team

  • Tradier is an API-driven online broker dealer, providing independent software developers with the ability to easily embed trading and market data into their applications. Learn more at www.tradier.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      Charlotte, NC

    • Year Invested

      2014

    • Team

  • Transave is focused on improving the treatment of serious lung diseases through the company’s next generation, proprietary liposomal delivery technology. Transave was acquired by Insmed Inc.

     

    • Category

      • Therapeutics
    • Status

      • Acquired
    • Location

      Monmouth Junction, NJ

    • Year Invested

      2006

    • Team

  • TreeENT is a Hangzhou, China-based operator of private, premium-positioned ambulatory surgery centers (ASCs) focused on high volume, high unmet need, and self-pay surgery markets.

    Learn more at treeent.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Hangzhou, China

    • Year Invested

      2019

    • Team

  • Trivitron Healthcare is India’s largest, national wholesale distributor and after-sales support provider of medical equipment and devices. Learn more at www.trivitron.com.

  • Turnstone Biologics (NASDAQ: TSBX) is transforming patient care with a new class of targeted viral immunotherapies to fight cancer.  Learn more at www.turnstonebio.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Ottawa, Canada

    • Year Invested

      2016

    • Team

  • Ultragenyx (NASDAQ: RARE) a biopharmaceutical company committed to bringing to patients novel products for the treatment of serious rare and ultra-rare genetic diseases. Learn more at www.ultragenyx.com.

    • Category

      • Therapeutics
    • Status

      • Public
    • Location

      Novato, CA

    • Year Invested

      2011

    • Team

  • Unbxd applies artificial intelligence and advanced data sciences to connect e-commerce shoppers to the products they are most likely to buy.  Learn more at www.unbxd.com. 


    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Mountain View, CA

    • Year Invested

      2017

  • Unison is the leading provider of home ownership investments, modernizing home financing through long-term partnerships. Unison works with lenders, regulators and institutional investors to integrate home ownership investing into the U.S. housing finance system. Unison HomeBuyer helps purchasers buy the home they want with less debt and risk, typically by doubling the down payment. The larger down payment makes it easier to qualify for a loan, increases buying power, lowers the monthly payment and/or allows a buyer to reserve cash. Unison HomeOwner provides current homeowners with cash to eliminate debt, remodel, pay for school, invest or use as a cash cushion, without the added debt or payments of a home equity loan or HELOC. Learn more at www.unison.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2018

    • Team

  • US HealthVest provides specialized, high quality psychiatric care, including substance abuse treatment, through a broad range of inpatient and outpatient programs. Learn more at www.ushealthvest.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2013

    • Team

  • Valor Performance is the premier digital learning platform focused on sustaining performance for executives and sales leaders. Valor’s software platform delivers personalized and research-based exercises as well as dedicated Valor coaches, who integrate the latest research on stress management and burnout with the insights of world-class athletes. Valor Performance was acquired by Mursion in 2024.

    • Category

      • Health IT/Services
    • Status

      • Acquired
    • Location

      Boston, MA

    • Year Invested

      2017

    • Team

  • Founded in 2018, VALR is a global cryptocurrency exchange serving over 1,000 corporate and institutional clients and close to 700,000 users worldwide. Headquartered in Johannesburg, VALR is licensed by the Financial Sector Conduct Authority (FSCA) in South Africa, approved to offer services in Europe, and has received initial approval from Dubai’s VARA. Learn more at valr.com.

  • Vendr is an end-to-end SaaS purchasing & renewal management platform. They manage your software purchases and renewals, so you can manage your business. Learn more at www.vendr.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2019

    • Team

  • Verid developed a knowledge-based authentication platform helping businesses to authenticate consumers through a series of questions. Verid was acquired by EMC in 2007.

    • Category

      • Enterprise IT
    • Status

      • Acquired
    • Location

      Ft. Lauderdale, FL

  • Verve Therapeutics (NASDAQ: VERV) is a biotechnology company created with a singular focus: to protect the world from heart disease. Verve is developing therapies to safely edit the genome of adults and confer lifelong protection from coronary artery disease, the most common form of heart disease and the leading cause of death worldwide. Learn more at www.vervetx.com.

  • Vestwell is a digital platform that makes it easier to offer and administer 401(k) plans. Vestwell removes traditional friction points through a seamless plan design, automated onboarding, streamlined administration, and flexible investment strategies, all at competitive pricing. By acting as a single point of contact, Vestwell has modernized the retirement offering while keeping the plan sponsor’s and plan participant’s best interests in mind.  Learn more at www.vestwell.com.

    • Category

      • FinTech
    • Status

      • Private
    • Location

      New York, NY

    • Year Invested

      2016

    • Team

  • Vicept Therapeutics is a dermatology specialty pharmaceutical company developing a topical prescription product for the treatment of the chronic skin condition, Rosacea. Vicept Therapeutics was acquired by Allergan.

     

  • ViewRay (NASDAQ: VRAY) designs, manufactures and markets the MRIdian® radiation therapy system. Which uses a high-definition MR imaging system designed from the ground up to address the unique challenges and clinical workflow for advanced radiation oncology.  Learn more at viewraysystems.com.

  • VitalWare makes the business of healthcare easier for providers through cloud-based SaaS solutions for analytics, documentation, coding, billing, and auditing technologies. VitalWare was acquired by Health Catalyst in 2020.

  • Wanhu provides integrated pharmacy benefit management services in China to better manage drug use and control costs. Learn more at www.wanhuhealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      China

    • Year Invested

      2017

    • Team

  • Warmly is the first AI-fueled pipeline acceleration platform that harnesses the power of existing sales enablement and intent tools to automatically identify high propensity website visitors and alert them to sales for real-time engagement. It’s the first such solution purpose built to meet the business and budget needs of SMBs. Learn more at www.warmly.ai.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Francisco, CA

    • Year Invested

      2020

    • Team

  • Welbe Health is a healthcare services company delivering coordinated and value-based care to medically frail seniors. Learn more at www.welbehealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      United States

    • Year Invested

      2015

    • Team

  • WellBeam transforms workflows between MD teams and their post-acute partners continuing the medical care of their patients. Through its EMR integrated solution, WellBeam reduces home health readmissions, drives provider wellness through less administrative workflow, and captures underbilled CMS codes available to providers. Learn more at www.well-beam.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Palo Alto, CA

    • Year Invested

      2021

    • Team

  • Wellframe is a Boston-based digital medicine company focused on building the next generation of infrastructure for clinical care delivery by combining artificial intelligence, medicine, and large scale computer systems. Learn more at www.wellframe.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Boston, MA

    • Year Invested

      2017

    • Team

  • Whatfix is a leading digital guidance and engagement platform that helps companies provide intuitive onboarding, and effective training and support. Whatfix’s contextual and personalized in-app content drives-up user productivity and engagement. Learn more at whatfix.com.

    • Category

      • Enterprise IT
    • Status

      • Private
    • Location

      San Jose, CA

    • Year Invested

      2019

    • Team

  • Wintermute is a global algorithmic liquidity provider for digital assets. Wintermute’s mission is to create liquid, efficient and transparent markets for institutional and retail investors across all vetted trading platforms and its own RFQ platform. Founded and managed by experienced traders and engineers from traditional financial markets, Wintermute brings the best practices of algorithmic and high-frequency trading into digital asset markets. Learn more at www.wintermute.com.

    • Category

      • Crypto
    • Status

      • Private
    • Location

      England, UK

    • Year Invested

      2021

    • Team

  • Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease. The company seeks to rethink the drug discovery and development process from end-to-end by bringing together leading talent across three core areas: machine learning research to better understand biology, expansive data generation to power new models, and robust therapeutic product development to treat disease. Learn more at www.xaira.com.

  • Xilio Therapeutics (NASDAQ: XLO) is a biotechnology company advancing next-generation cancer immunotherapies designed to improve patient outcomes by unleashing the power of the immune system selectively at the site of the tumor. Learn more at www.xiliotx.com.

  • Xoom is a digital money transfer company that allows users to securely transfer money online. Xoom went public in 2013 and was then acquired by PayPal in 2015. Learn more at www.xoom.com.

    • Category

      • FinTech
    • Status

      • Acquired
    • Location

      San Francisco, CA

  • Zeen Health is a health IT company developing prescription digital therapeutics (PDT) for various mental health disorders. Learn more at zeenhealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Shenzhen, China

    • Year Invested

      2021

    • Team

  • Zenflow is a medical device company developing the Spring Implant for patients with benign prostate hyperplasia (BPH). Learn more at www.zenflow.com.

  • Creating the industry’s first shared development platform backed by a shared data record, Zus aims to bring about a better health data reality by empowering a wave of new, digital-first healthcare builders who will create digital health technologies and services that are cheaper, more customizable, and more personalized. This vision drives Zus to proactively connect the largest array of traditional medical providers to novel health data sources so that health data becomes frictionless to use.  Learn more at www.zushealth.com.

    • Category

      • Health IT/Services
    • Status

      • Private
    • Location

      Watertown, MA

    • Year Invested

      2021

    • Team

The list includes investments made by funds managed by F-Prime. The companies are listed in alphabetical order. The list of investments is updated quarterly and, as such, may not reflect most recent F-Prime investments. This list also excludes companies that are currently in stealth.