Rezera

Developing small molecule inhibitors of the NLRP3 inflammasome.

Sector

Life Sciences

Category

Therapeutics

Location

Cambridge, United Kingdom

Initial Investment

2018
Developing small molecule inhibitors of the NLRP3 inflammasome.

Rezera, formely Nodthera, is a clinical-stage biotechnology company developing a portfolio of internally-invented and wholly-owned oral inhibitors of NLRP3 to address inflammatory drivers of cardiovascular and neurologic diseases driven by the NLRP3 inflammation pathway. The Company’s lead program, ruvonoflast (f/k/a NT-0796), completed its Phase 2 RESOLVE-1 and RESOLVE-2 trials. The Company is also advancing trabzanoflast (f/k/a NT-0150) for treatment of neurologic diseases.

Rezera is headquartered in Boston, Massachusetts, with an R&D base in Cambridge, UK.