Healthcare

We create and invest in leading companies in therapeutics, medtech, and health IT & services.

18

Eighteen products and drugs approved

With another 13 drugs in phase 3. Typically, only 1 in 5,000 drugs makes it from idea to market.

17

Seventeen companies created from scratch

If we can't find a company solving an important problem, we create one ourselves - just like we did with Innovent, Denali, and Beam to name a few.

$1.8B

Nearly two billion dollars over seven funds

Without the pressure of fundraising from outside investors, we're privileged to champion companies that help heal the world.

Category

Region

Status

  • Proteostasis Therapeutics (NASDAQ: PTI)  is a drug discovery company developing small molecule therapeutics to treat cystic fibrosis and other diseases caused by dysfunctional protein processing. Learn more at www.proteostasis.com.

    • Category

      • Therapeutics

    • Status

      • Public

    • Location

      Cambridge, MA

    • Year Invested

      2008

    • Team

      Stephen Knight, M.D.

  • Pulmocide is a biopharmaceutical company with a mission to treat common acute and chronic respiratory tract infections associated with serious complications and devastating effects on patients’ quality of life. Learn more at www.pulmocide.com.

  • Quartet Health is developing care coordination software and services designed to improve clinical outcomes and reduce the cost of care for patients where behavioral health is the primary or a comorbid condition. Learn more at www.quartethealth.com

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      New York, NY

    • Year Invested

      2015

    • Team

      Carl Byers

  • ReGenX Biosciences (NASDAQ: RGNX)  is a leading AAV (adeno-associated virus) gene therapy company with a broad platform technology based on its proprietary NAV vector technology platform Learn more at www.regenxbio.com.

    • Category

      • Therapeutics

    • Status

      • Public

    • Location

      Washington, D.C.

    • Year Invested

      2013

  • RespiVert was a drug discovery and development company focused on inhaled therapies for severe respiratory disease. RespiVert was acquired by Centocor Ortho Biotech – a division of Johnson & Johnson.

    • Category

      • Therapeutics

    • Status

      • Acquired

    • Location

      London, UK

    • Year Invested

      2007

    • Team

      Stephen Knight, M.D.

  • Sana Biotechnology, Inc. is focused on creating and delivering engineered cells as medicine for patients. We are a team of scientists, clinicians and biotechnology veterans focused on creating an enduring company that makes meaningful medicines and changes how we approach treating disease. Learn more about Sana at www.sana.com.

  • Semma Therapeutics is a regenerative medicine company founded to develop transformative stem cell-derived therapies to provide a functional cure for patients with diabetes. This company was acquired by Vertex in 2019.

  • ShouTi is an early-stage, GPCR-based  drug discovery company focused on novel small molecules for multiple unmet medical needs.

  • Singular Genomics is developing a new next generation sequencing platform. Learn more at www.singulargenomics.com.

  • 66nao provides a cloud based platform for digital brain assessment and training. Learn more at www.66nao.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Beijing, China

    • Year Invested

      2016

  • Stride Health is an early-stage healthcare IT company developing a multi-carrier, private health insurance marketplace for the individual segment. Learn more at www.stridehealth.com.

    • Category

      • FinTech
      • Health IT/Services

    • Status

      • Private

    • Location

      San Francisco, CA

    • Year Invested

      2014

    • Team

      Carl Byers, Hannah Arnold

  • Surface Oncology (NASDAQ:SURF) is an immuno-oncology company developing next-generation antibody therapies focused on the tumor microenvironment with lead programs targeting CD73, CD39, IL-27 and CD47.  Learn more at www.surfaceoncology.com.

  • Symbiomix developed the first oral, single dose treatment in the United States for bacterial vaginosis (BV), a common gynecological infection that increases the risk of serious health problems. Symbiomix was acquired by Lupin Pharmaceuticals. Learn more at www.symbiomix.com.

    • Category

      • Therapeutics

    • Status

      • Acquired

    • Location

      Newark, NJ

    • Year Invested

      2013

    • Team

      Thomas Beck, M.D.

  • TCT Medical is a diagnostic company based in China which provides high quality diagnostic tests, primarily in the women’s health arena. TCT Medical was acquired by Hologic.

    • Category

      • MedTech

    • Status

      • Acquired

    • Location

      Beijing, China

    • Year Invested

      2009

    • Team

      Stephen Knight, M.D.

  • Tempest Therapeutics is a development-stage biotechnology company advancing small molecule therapeutics that modulate anti-tumor immunity pathways. Learn more at www.tempesttx.com.

  • Tetraphase (NASDAQ: TTPH)  is a biopharmaceutical company using its proprietary chemistry technology to create novel antibiotics for serious and life-threatening bacterial infections; its lead product XERAVATM (eravacycline) is approved for the treatment of complicated intra-abdominal infections by the FDA and EMA. Learn more at www.tphase.com.

  • Topaz Pharmaceuticals is a specialty pharmaceutical company developing a topical prescription product, Sklice, for the treatment of head lice. Topaz Pharmaceuticals was acquired by Sanofi.

     

  • TraceLink the world’s largest Track and Trace Network for connecting the life sciences supply chain and providing real-time information sharing for better patient outcomes. Learn more at www.tracelink.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Wakefield, MA

    • Year Invested

      2015

    • Team

      Jon Lim

  • Transave is focused on improving the treatment of serious lung diseases through the company’s next generation, proprietary liposomal delivery technology.

     

    • Category

      • Therapeutics

    • Status

      • Public

    • Location

      Monmouth Junction, NJ

    • Year Invested

      2006

    • Team

      Robert Weisskoff, Ph.D.

  • TreeENT is a Hangzhou, China-based operator of private, premium-positioned ambulatory surgery centers (ASCs) focused on high volume, high unmet need, and self-pay surgery markets.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Hangzhou, China

    • Year Invested

      2019

    • Team

      Carl Byers, Kevin Chu

  • Trivitron Healthcare is India’s largest, national wholesale distributor and after-sales support provider of medical equipment and devices. Learn more at www.trivitron.com.

  • Turnstone Biologics is transforming patient care with a new class of targeted viral immunotherapies to fight cancer.  Learn more at www.turnstonebio.com.

    • Category

      • Therapeutics

    • Status

      • Private

    • Location

      Ottawa, Canada

    • Year Invested

      2016

  • Ultragenyx (NASDAQ: RARE) a biopharmaceutical company committed to bringing to patients novel products for the treatment of serious rare and ultra-rare genetic diseases. Learn more at www.ultragenyx.com.

    • Category

      • Therapeutics

    • Status

      • Public

    • Location

      Novato, CA

    • Year Invested

      2011

    • Team

      Stephen Knight, M.D.

  • Unum (NASDAQ:UMRX) has built an antibody-coupled T-cell receptor (ACTR) platform that, when combined with tumor-specific antibodies, directs an individual’s cytotoxic T-lymphocytes (CTLs) to kill tumor cells. Learn more at www.unumrx.com.

    • Category

      • Therapeutics

    • Status

      • Public

    • Location

      Cambridge, MA

    • Year Invested

      2014

  • US HealthVest provides specialized, high quality psychiatric care, including substance abuse treatment, through a broad range of inpatient and outpatient programs. Learn more at www.ushealthvest.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      New York, NY

    • Year Invested

      2013

    • Team

      Jon Lim

  • Valor Performance is the premier digital learning platform focused on sustaining performance for executives and sales leaders. Valor’s software platform delivers personalized and research-based exercises as well as dedicated Valor coaches, who integrate the latest research on stress management and burnout with the insights of world-class athletes. Learn more at www.valorperform.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Boston, MA

    • Year Invested

      2017

    • Team

      Carl Byers

  • Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Verve is developing therapies to safely edit the genome of adults and confer lifelong protection from coronary artery disease, the most common form of heart disease and the leading cause of death worldwide. Learn more at www.vervetx.com.

  • Vicept Therapeutics is a dermatology specialty pharmaceutical company developing a topical prescription product for the treatment of the chronic skin condition, Rosacea. Vicept Therapeutics was acquired by Allergan.

     

  • ViewRay (NASDAQ: VRAY) designs, manufactures and markets the MRIdian® radiation therapy system. Which uses a high-definition MR imaging system designed from the ground up to address the unique challenges and clinical workflow for advanced radiation oncology.  Learn more at www.viewray.com.

  • VitalWare makes the business of healthcare easier for providers through cloud-based SaaS solutions for analytics, documentation, coding, billing, and auditing technologies. Learn more at www.vitalware.com.

  • Wanhu provides integrated pharmacy benefit management services in China to better manage drug use and control costs. Learn more at www.wanhuhealth.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      China

    • Year Invested

      2017

    • Team

      Chong Xu, Ph.D.

  • Welbe Health is a healthcare services company delivering coordinated and value-based care to medically frail seniors. Learn more at www.welbehealth.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      United States

    • Year Invested

      2015

    • Team

      Jon Lim, Carl Byers

  • WellAir is a global company working to disinfect and purify indoor air for optimal human health and building performance. Learn more at www.wellairsolutions.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Dublin, Ireland

    • Year Invested

      2014

    • Team

      Jon Lim, Brett Cook

  • Wellframe is a Boston-based digital medicine company focused on building the next generation of infrastructure for clinical care delivery by combining artificial intelligence, medicine, and large scale computer systems. Learn more at www.wellframe.com.

    • Category

      • Health IT/Services

    • Status

      • Private

    • Location

      Boston, MA

    • Year Invested

      2017

    • Team

      Carl Byers

  • Zenflow is a medical device company developing the Spring Implant for patients with benign prostate hyperplasia (BPH). Learn more at www.zenflow.com.