Blog

F-Prime Capital ranked #2 in top 100 biotech VCs

2015 proved to be the biggest year on record for venture investing in U.S. biotechs. A total of $7.7 billion flowed into a range of startups, some clustered in Boston/Cambridge and San Francisco, but with quite a large amount finding its way to drug developers off the beaten biotech path.

This year the money has continued to flow at the same torrid pace, even though the IPO window for drug developers has dropped down to an uncomfortable squeeze space for the hottest, or most desperate, companies to aim at.

But how do the VCs rank in terms of deals and dollars? I asked Thomson Reuters, which does the numbers for the MoneyTree Report from PricewaterhouseCoopers LLP and the National Venture Capital Association, and they came back with the list below.

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Stem cell factory opens door for trials of personalized diabetes treatment

In a step that could lead to a new diabetes treatment, several Boston-area hospitals have teamed up with the Harvard Stem Cell Institute and biotech Semma Therapeutics to make personalized cell-based therapies and organize clinical trials.

It is one of several initiatives around the country aimed at manufacturing cell-derived treatments, as the hope for such therapies creates a demand for the production of the cells.

In patients with type 1 diabetes, the immune system attacks the pancreatic cells that produce insulin, called beta cells. Doctors have for years transplanted beta cells from dead donors into patients, but the supply is insufficient for the millions of people with type 1 diabetes, and patients’ bodies sometimes reject the donor cells.

The new program, officially called the Boston Autologous Islet Replacement Program, could provide enough high-quality beta cells needed to treat patients in upcoming clinical trials. And the cells that will be transplanted into these volunteers will be derived from their own blood cells, cutting the risk of rejection.

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Tradier names noted fintech industry leader Stephen Ehrlich as its new CEO

Tradier, Inc., an industry leader in providing next generation brokerage solutions that enable Platform Providers and Developers, Digital Advisors, Registered Investment Advisors and Registered Broker-Dealers to offer trading access to the US Markets through its bundled APIs from their platforms, today announced that Stephen Ehrlich has been named as its next Chief Executive Officer as of June 1st 2016.

Mr. Ehrlich succeeds Founder Dan Raju who will assume the role of the Executive Chairman and Chief Information and Product Officer. Mr. Ehrlich has had a distinguished 25-year career in the financial services industry serving global retail and institutional investors and traders. Previously, he was the CEO and Founder of Lightspeed Financial and under his leadership Lightspeed expanded to become the fourth largest volume based retail broker-dealer. Prior to Lightspeed, Mr. Ehrlich was the CEO of the E*TRADE Professional Trading Group. At E*TRADE he played a pivotal role in Brokerage Strategy, Product and Services.

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TradeBlock provides Cumberland Mining with Order Management, Execution Tool

TradeBlock is now the order management system and execution tool set for Cumberland Mining, an affiliate of principal trading firm DRW. Cumberland is provider of liquidity in bitcoin and ether digital currency markets.

The rapid growth of institutional digital currency trading has driven demand for a variety of products and services. The over-the-counter (OTC) digital currency market is growing rapidly by providing a network of deep, instant liquidity directly between institutions and their counterparties.

TradeBlock provides professional clients in digital currency markets with trade management tools, wallet integrations, KYC/AML automation, accounting tools, and exportable records, all on top of a suite of market and blockchain data.

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Iora Health named an innovator in primary care

There is an urgent need for innovation in primary care delivery — inadequate access for patients, poor care coordination, and a broken reimbursement system are well-documented challenges facing the field. Despite promising efforts and important pilots to overcome these obstacles, wide-spread innovation and improvement has been constrained by financing structures that incent the piecemeal, volume-driven delivery of clinical services rather than promoting care redesign. Amidst these prevailing reimbursement models, sources of funding for innovation in primary care delivery are limited.

In recent years, a handful of primary care leaders, dissatisfied with the pace of change, have approached the structure and financing of primary care transformation through a radically different model: for-profit, venture capital-funded enterprises. And many leading investors from the traditional health care spaces of biotech and pharmaceuticals—such as F-Prime Capital Partners, Maverick Capital, Polaris Ventures, and GV—have funded primary care service enterprises.

To better characterize this growing trend, we used publically available information to explore how three prominent innovators—Iora Health, One Medical Group, and Qliance Medical Management—are leveraging venture funding to support primary care redesign.

 

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Flywire launches cross-border payment service in Japan

Flywire, a leading provider of cross-border payment solutions, today announced its expansion into Japan. Operating as Flywire GK and based in Tokyo, the company will serve the increasing number of educational institutions in Japan attracting foreign students, as well as Japanese students studying abroad. The move builds on Flywire’s recently launched operations in Shanghai, China and broader business expansion across the Asia-Pacific region including Australia and Singapore.

“Japan is one of the key countries in Flywire’s APAC expansion and we are investing significantly there to help Japanese educational institutions make the payment process easy, efficient and transparent for their international students,” said Mike Massaro, CEO at Flywire. “We have an outstanding local team in place there with years of experience in the education and payments business.”

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Vermont to employ PatientPing to coordinate care

As part of the Vermont Health Care Innovation Project, the Green Mountain State has tapped Boston-based PatientPing for data exchange among its hospitals.

Vermont officials and healthcare professionals will announce the adoption of PatientPing across the state’s healthcare providers today at Vermont Blueprint for Health 2016 in Burlington.

The technology is expected to boost medical information transparency among previously disconnected healthcare providers.

“Our state has come together in this partnership to launch a progressive initiative dedicated to improving the way Vermonters receive care,” said Lawrence Miller, senior advisor and chief of healthcare reform at the Office of the Governor, in a news release.

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Acacia Pharma initiates second phase e treatment trial with BAREMSIS™, expects NDA filing in 2016

Acacia Pharma Group plc (“Acacia Pharma”), the supportive care company developing products for US and international markets, announces the initiation of its second pivotal Phase 3 treatment study, investigating BAREMSIS (amisulpride injection, formerly APD421) in surgical patients who develop post-operative nausea & vomiting (PONV), despite having received antiemetic prophylaxis before surgery.

International consensus guidelines recommend that surgical patients who develop PONV should be treated with an antiemetic with a different mechanism of action from any antiemetic given before surgery for the prevention of PONV. Currently two classes of antiemetics are predominantly given prophylactically in an attempt to prevent PONV. These are 5HT3 antagonists (usually ondansetron) and corticosteroids (usually dexamethasone). A safe and effective third antiemetic mechanism is therefore required to treat subsequent PONV and BAREMSIS, a dopamine antagonist antiemetic, could fulfil this need.

 

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VitalWare Completes Financing to Accelerate Growth of SaaS Solutions for Healthcare Providers

VitalWare™, a leading provider of revenue cycle SaaS solutions to healthcare organizations, announced today that it has received a growth investment from F-Prime Capital Partners (formerly Fidelity Biosciences), a global venture capital firm investing in healthcare and technology.

Since its founding in 2011, VitalWare has created and launched six SaaS products to build an intuitive suite of cloud-based Analytics, Documentation, Coding, Billing and Auditing technologies.  The backbone of this suite is the patent-pending, proprietary medical terminology engine, ICD Sherpa™, which guides physicians, clinical documentation staff and coders through the increased specificity requirements found in the new ICD-10 code set. VitalWare is the only vendor that provides a technology that enables consistent search results to all three of these major constituents. The Company was recently ranked #123 on the 2015 Inc. 500 list of the fastest-growing private companies in America.

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Baxalta and Precision BioSciences form Global Genome Editing Collaboration in Immuno-Oncology

Baxalta Incorporated (NYSE: BXLT), a global biopharmaceutical leader dedicated to delivering transformative therapies to patients with orphan diseases and underserved conditions, and Precision BioSciences, the genome editing company, today announced a global collaboration to develop a broad series of allogeneic chimeric antigen receptor (CAR) T cell therapies directed towards areas of major unmet need in multiple cancers.

 

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